Human Immunodeficiency Virus Type 1 (HIV-1) Trofile Co-Receptor Tropism LG5434 - Cancel and Reorder as LSMISC


Sunquest Code:TROTRP  
Epic Code:LAB6664Epic Name:Trofile Co-Receptor Tropism
Order Instructions:Order as LSMISC, not as ARMISC.
Synonyms:Tropism
Methodology:Recombinant virus, single replication
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 16-23 days.
Special Instructions:Provide the patient's HIV 1 Viral Load.
Procedure should be used for patients with documented HIV-1 infection and viral loads greater than 1000 copies/mL.


Collection Instructions

Specimen:Blood
Optimal Volume:6.2 mL
Container:Purple (EDTA)
Causes for Rejection:Thawed specimens.


Processing and Shipping

Specimen Processing:Within 6 hours of collection, centrifuge and aliquot 3 mL plasma. Freeze immediately.
Shipping Instructions:Ship on dry ice. CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Stability:2 weeks frozen at -20.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:3001246


Interpretive

Reference Range:By report.
Use:
For patients wtih HIV-1 viral loads ≥ 1000 copies/mL.
The US Department of Health and Human Serices (DHHS) and the Infectious Diseases Society of America (IDSA) guidelines recommend that a coreceptor tropism test be performed whenever the use of CCR5 inhibitor is being considered. Coreceptor tropism testing might also be considered for patients who exhibit virologic failure on a CCR5 inhibitor.


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