Hepatitis B Core Antibody
| Sunquest Code: | HBCAB | ||
| Epic Code: | LAB3514 | Epic Name: | Hepatitis B Core Antibody |
| Synonyms: | Hep B Core; HBCAB; HepB | ||
| Methodology: | Chemiluminescent immunoassay | ||
| Test Includes: | Hepatitis B core antibody: if positive Hepatitis B surface antibody will be performed. If Hepatitis B surface antibody is negative, Hepatitis B core IgM antibody will be performed. | ||
| Turnaround Time: | Performed Mon-Fri; negative results are reported the same day, positive results are reported within 3 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.4 mL |
| Container: | Red or gold (gel) (Blue Na Citrate, 3.2% - fill to fill line on tube, Green (lithium heparin, gel), Purple (EDTA), Red (no gel)) |
| Collection Instructions: | Serum is preferred. EDTA, heparinized or citrated plasma will be accepted. Serum is the only acceptable sample for neonates. |
| Causes for Rejection: | Gross hemolysis, turbidity |
Processing and Shipping
| Specimen Processing: | Within 2 hours of collection, centrifuge and leave sample in serum separator tube. If necessary, aliquot 0.4 mL, 0.1 mL minimum. |
| Shipping Instructions: | Ship at refrigerated or frozen temperature. |
| Stability: | After separation from cells: Up to 7 days refrigerated. Freeze aliquot sample if stored for more than 7 days. |
| Test Performed at or Referral Lab | Specialty Core (UMMC-East Bank) |
Interpretive
| Reference Range: | Non-reactive |
| Use: | HBc antibodies can be used to monitor the progress of hepatitis B infection. It is present in serum shortly after the appearance of hepatitis B surface antigen and will persist for life. |
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