Genetic Renal Panel to MORL - LG5797


Sunquest Code:LSMISC  
Epic Code:LAB4909Epic Name:Send Outs Misc Test
Synonyms:Hemolytic Uremic Syndrome; aHUS; Atypical Hemolytic Uremic Syndrome; Complement Kidney Genes; Thrombotic Microangiopathies; Complement Nephropathy Gene Analysis
Methodology:Next generation sequencing and Multiple Ligation Probe Amplification
Turnaround Time:Specimens are sent to the reference laboratory Mon-Thurs; results are reported within 3 weeks
Special Instructions:A completed requisition must accompany each specimen.  See associated links.  Samples are accepted Mon-Friday only.  Do not send samples for weekend delivery or the day before a holiday.
Associated Links:

MORL Kidney Testing Requisition



Collection Instructions

Specimen:Blood
Optimal Volume:10 mL adult or 4 mL for children under 4 years of age
Minimum\Peds Volume:8 mL adult; 3 mL for children under 4 years of age.
Container:Purple (EDTA)
Causes for Rejection:Frozen or clotted specimen, incorrect anticoagulant, specimen more than 7 days old.


Processing and Shipping

Specimen Processing:Whole blood  Do not process. Store at room temperature or if shipping is delayed refrigerate.
Shipping Instructions:Ship overnight at room temperature.  Protect from temperature extremes.  Do not freeze.
Stability:1 week refrigerated
Test Performed at or Referral Lab Lab Sendouts  (University Iowa Molecular Otolaryngology & Renal Research Laboratories)
Referral Lab number:GRP07


Interpretive

Reference Range:By report.
Use:
Screens 12 genes (CFH, CFI, MCP, CFB, CFHR5, C3, THBD, ADAMTS13, DGKE, MMACAHC, G6PD and PLG) known to be associated with the thrombotic microangiopathies: Hemolytic Uremic Syndrome, atypical Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura.  The panel utilizes custom-targeted sequence capture for DNA enrichment followed by massively parallel DNA sequencing.  Multiple Ligation Probe Amplification of the CFH-CFHR5 genomic region is also performed as part of this panel.


Click HERE to Report test errors or omissions.
*If no email program is associated with this computer, please contact:
systemlabguide@fairview.org for TestID: 5797"