Saccharomyces cerevisiae Antibodies, IgG & IgA - LG6098


Sunquest Code:ARMISC  
Epic Code:LAB4909Epic Name:Send Outs Misc Test
Methodology:Semi-quantitative enzyme-linked immunosorbent assay
CPT Code:86671 x2
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-2 days.


Collection Instructions

Specimen:Blood
Optimal Volume:1 mL
Minimum\Peds Volume:0.8 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Contaminated, heat-inactivated, hemolyzed or severely lipemic specimens.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot within 2 hours of collection 0.5 mL, 0.3 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:50564


Interpretive

Reference Range:

Saccharomyces cerevisiae Antibody IgG

20.0 Units or less: Negative

20.1-24.9 Units: Equivocal

25.0 Units or greater: Positive

Saccharomyces cerevisiae Antibody IgM

20.0 Units or less: Negative

20.1-24.9 Units: Equivocal

25.0 Units or greater: Positive

 

 

Use:Aids in differentiating Crohn disease from ulcerative colitis in individuals with inflammatory bowel disease. Saccharomyces cerevisiae IgG antibodies are found in 60-70% of Crohn disease (CD) patients and 10-15% of ulcerative colitis (UC) patients. Saccharomyces cerevisiae IgA antibodies are found in about 35% of CD patients but less than 1% of UC patients. Detection of both Saccharomyces IgG and IgA antibodies in the same serum specimen is highly specific for CD.


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