Epidermal Nerve Fiber

Sunquest Code:ENF  
Epic Code:LAB6605Epic Name:Epidermal Nerve Fiber Density
Order Instructions:Only one Epidermal Nerve Fiber order is required for multiple samples. Order one ENF and transport all biopsies together.
Synonyms:ENF; Skin Biopsy for Nerve Density; Confocal Microscopy
Methodology:Immunofluroescent localization of nerve/tissue antigens in skin sections, confocal microscopy, tracing and quantification of epidermal nerve fibers, report of nerve fiber density, general innervation morphology
CPT Code:88314, 88305, 88346, 88348, 88356, 883501 x5
Turnaround Time:Specimens are sent to reference laboratory Mon-Thur; results are reported within 14 days,
Special Instructions:STAT processing required. Sample must be in Zamboni fixative within 4 hours and arrive in performing lab within 24 hours. Place tissues directly into Zamboni fixative (request from Kennedy Lab (612-625-1431) immediately upon excision and send to UMMC-East Core Lab for delivery to the Kennedy Laboratory, J-119 Diehl Hall.

Collection Instructions

Specimen:Tissue-Skin Biopsy
Optimal Volume:3 mm
Collection Instructions:Place tissues directly into Zamboni fixative-containing vial immediately upon excision. Place vial with specimen in styrofoam container with an ice pack.
Causes for Rejection:Damaged tissue, frozen tissue, tissue not in fixative.

Processing and Shipping

Specimen Processing:STAT processing required. See Special Instructions. Place tissues directly into Zamboni fixative-containing vial upon excision, Place vial with specimen in Styrofoam container with an ice pack.
Shipping Instructions:Ship at refrigerated temperatures. Do not freeze.
Test Performed at or Referral Lab Lab Sendouts  (Kennedy Lab, J-119 Diehl Hall)

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