West Nile Virus Antibody, IgG by ELISA, CSF


Sunquest Code:CWNG  
Epic Code:LAB6831Epic Name:West Nile Virus Ab, IgG CSF
Synonyms:Arbovirus
Methodology:Enzyme linked immunosorbent assay
CPT Code:86789
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-6 days.
Compliance:

This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.



Collection Instructions

Specimen:CSF
Optimal Volume:2 mL
Minimum\Peds Volume:0.15 mL
Container:Sterile tube (Plastic leakproof container, sterile)
Causes for Rejection:Heat inactivated or hemolyzed specimens.


Processing and Shipping

Specimen Processing:Aliquot 2 mL, 0.15 mL minimum CSF into a sterile container. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:50238


Interpretive

Reference Range:

1.29 IV or less

Negative. No significant level of West Nile virus IgG antibody detected.

1.30-1.49 IV

Equivocal. Questionable presence of West Nile virus IgG antibody detected. Repeat testing in 10-14 days may be helpful.

1.50 IV or greater

Positive. Presence of IgG antibody to West Nile virus detected, suggestive of current or past infection.

 

 

Use:The detection of antibodies to West Nile virus in cerebrospinal fluid may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer or serum antibodies across the blood-brain barrier.


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