Abbott i-Stat Activated Clotting Time - Point of Care Testing


Sunquest Code:ACT  
Epic Code:POC200Epic Name:Activated Clotting Time POCT
Methodology:Activated whole blood clotting time
Turnaround Time:Performed daily; results are available immediately.
Special Instructions:Call the lab to schedule/order laboratory performed testing at the bedside


Collection Instructions

Specimen:Whole Blood
Optimal Volume:0.2 mL
Minimum\Peds Volume:0.04 mL
Container:See Collection Instructions, Plain syringe (ACT cartridge available from laboratory)
Collection Instructions:Venipuncture Collection: Use two plain syringes to minimize thromboplastin contamination. Collect 2 mL into the first syringe and discard, into the second syringe collect 0.2 mL to be used for testing. Do not use heparinized syringes. Catheter Collection: Flush anticoagulated catheter with 5 mL of saline. Collect 5-10 mL and discard, into a second plain syringe collect 0.2 mL to be used for testing.
Causes for Rejection:Extraneous heparin present in the sample; heparinized syringes; samples not collected immediately prior to testing.
Contraindications:Testing should be performed immediately. If there is a delay in testing or a repeat measurement is needed, a fresh sample must be collected.


Processing and Shipping

Stability:For questions, contact the laboratory at your facility.
Test Performed at or Referral Lab Point of Care  (UMMC-West Bank, UMMC-East Bank, Fairview Ridges - FRH, Fairview Southdale - FSH)


Interpretive

Reference Range: 75-150 seconds
Therapeutic Range:Dependent on clinical procedure.
Sheath Pull Guidelines:  
  • If value is < 180 seconds, no further testing is required. The laboratory places orders for follow-up testing if the result is >180 seconds.
  • If value is greater than 180, repeat ACT in 60 minutes.
  • If value changed by less than 6 seconds, recommend a heparin 10a level. Rare patients may have a baseline ACT above 150 seconds and heparin 10a level of less than 0.10 IU/mL, indicating little or no heparin is present in the sample.

Testing Guidelines for PRISMA Patients:
  • 160-180 seconds for normal heparin.
  • 140-150 for minimal heparin
 
Use:Monitor a patient's anticoagulation state during high dose heparin administration.


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