Dermatomyositis Panel


Sunquest Code:DMYOPN  
Epic Code:LAB6956Epic Name:Dermatomyositis Panel
Methodology:Immunoprecipitation, Immunoblot
CPT Code:83516 x6
Test Includes:Mi-2 (nuclear helicse protein) Antibody, P155/140 (TIF1-gamma) Antibody; SAE1 (SUMO activating enzyme) Antibody; MDA5 (CADM-140) Antibody; NXP-2 (Nuclear matrix protein-2) Antibody; TIF1-gamma (TIF1-y) Antibody
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 7-15 days.
Compliance:

This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.



Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:1.2 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Hemolyzed, hyperlipemic, icteric heat-treated or contaminated specimens.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot within 2 hours of collection, 1 mL, 0.5 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:Stability: Samples are stable for 48 hours at room temperature; 2 weeks refrigerated; and 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2013991


Interpretive

Reference Range:

Mi2 (nuclear helicase protein) Antibody

Negative

P155/140 (TIF1-gamma) Antibody

Negative

SAE1 (SUMO activating enzyme) Antibody

Negative

MDA5 (CADM-140) Antibody

Negative

NXP-2 (Nuclear matrix protein-2) Antibody

Negative

TIF1-gamma (TIF1-y) Antibody

Negative

 

 

Use:Evaluation of patients with characteristic cutaneous manifestations of dermatomyositis with or without muscle weakness.


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