Helicobacter pylori Breath Test, Pediatric


Sunquest Code:HPBTP  
Epic Code:LAB8015Epic Name:Helicobacter pylori Breath Pediatric
Synonyms:H. pylori; Breath Tek; 13C Urea Breath Test; Ulcer Breath Test; H pylori; UBT
Methodology:Spectrophotometry
CPT Code:----------CPTCODES HERE----------
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 4 days.


Collection Instructions

Specimen:Breath
Collection Instructions:Use BreathTek UBT kit (ARUP supply #51124); available online through eSupply using ARUP Connect or contact ARUP Client Services at (800) 522-2787.
  • Label breath collection bags with patient name, MRN, date and time of collection, and indicate Pre (blue) or Post (pink).
  • Collect the baseline (Pre) breath specimen according to the instructions in the BreathTek UBT kit.
  • After the allotted time, collect the Post breath specimen according to the instructions in the kit.
  • Information required: Record weight, height, gender and age.
Patient Preparation:This test requires the pediatric patient (3-17 years old) to fast and abstain from smoking for 1 hour prior to test administration. The patient should not have taken antibiotics, proton pump inhibitors (e.g. Prilosec, Prevacid, Aciphex, Nexium) or bismuth preparations (e.g. Pepto-Bismol) within the previous 14 days. When used to monitor treatment, the test should be performed four weeks after cessation of definitive therapy. The patient should be informed that the Pranactin-Citric drink that will be administered containes phenylalanine. Phenylketourics restrict dietary phenylalanine.
Causes for Rejection:Under-inflated bags. Specimens from patients younger than 3 years old. Refrigerated or frozen specimens.


Processing and Shipping

Specimen Processing:CRITICAL ROOM TEMPERATURE
Shipping Instructions:Ship at room temperature. Protect from temperature extremes.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2010925


Interpretive

Reference Range:A negative result does not rule out the possibility of H. pylori infection. If clinical signs are suggestive of H. pylori infection, retest with a new specimen or an alternate method. Know causes of false negative results include:
  • Use of antibiotics, proton pump inhibitors and bismuth preparations during the preceding 2 weeks.
  • Administration of the breath test less than 4 weeks after completion of definitive therapy to eradicate H. pylori.
  • Premature or late collection after the post-dose specimen.

Known causes of false positive results include:
  • Patients with achlorhydria
  • Rinsing the test solution in the mouth, which can allow contact with urease-positive bacteria.
  • The presence of other gastric spiral organisms such as Helicobacter heilmanii.
   
Limitations:For valid result, the post-breath specimen must be collected between 15 and 30 minutes after the patient drinnks the Pranactin-Citric solution.
Use:Use to diagnose H. pylori infection in children and adolescents (3 to 17 years of age). For adults, refer to Helicobacter pylori Breath Test, Adult.


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