Helicobacter pylori Breath Test, Adult


Sunquest Code:HPBTA  
Epic Code:LAB8014Epic Name:Helicobacter pylori Breath Adult
Synonyms:H pylori; H. pylori; BreathTek UBT; 13C Urea Breath Test; Ulcer Breath Test
Methodology:Spectrophotometry
CPT Code:----------CPTCODES HERE----------
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 4 days.


Collection Instructions

Specimen:Breath
Collection Instructions:Use BreathTek UBT kit (ARUP supply #51124) available online through eSupply using ARUP Connect or contact ARUP Client Services at (800) 522-2787.
  • Label breath collection bags with patient name, MRN, date and time of collection, and indicate Pre (blue) or Post (pink).
  • Collect the baseline (Pre) breath specimen according to the instructions in the BreathTek UBT kit.
  • After the allotted time, collect the Post breath specimen according to the instructions in the kit.
Do not allow patient to perform test. This test must be performed by a credentialed professional.
 
Patient Preparation:This test requires the adult patient (>17 years of age) to fast and abstain from smoking for 1 hour prior to test administration. The patient should not have taken antibiotics, proton pump inhibitors (e.g., Prilosec, Prevacid, Aciphex, Nexium) or bismuth preparations (e.g., Pepto-Bismol) within the previous 14 days. When used to monitor treatment, the test should be performed four weeks after cessation of definitive therapy. The patient should be informed that the Pranactin-Citric drink that will be administered contains phenylalanine. Phenylketourics restrict dietary phenylalanine.
Causes for Rejection:Underinflated bags. Specimens from patients younger than 18 years of age. Refrigerated or frozen samples.


Processing and Shipping

Specimen Processing:CRITICAL ROOM TEMPERATURE
Shipping Instructions:Ship at room temperature. Protect from temperature extremes.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2010476


Interpretive

Reference Range:A negative result does not rule out the possibility of H. pylori infection. If clinical signs are suggestive of H. pylori infection, retest with a new specimen or an alternate method. Know causes of false negative results include:
  • Use of antibiotics, proton pump inhibitors and bismuth preparations during the preceding 2 weeks.
  • Administration of the breath test less than 4 weeks after completion of defnitive therapy to eradicate H. pylori.
  • Premature or late collection of the post-dose specimen.
  Known causes of false postive results include:
  • Patients with achlorhydria
  • Rinsing the testing solution in the mouth, which can allow contact with urease-positive bacteria.
  • The presence of other gastric spiral organisims, such as Helicobacter heilmaii.
Limitations:For a valid result, the post-breath specimen must be collected between 15 and 30 minutes after the patient drinks the Pranactin-Citric solution.
Use:Use to diagnose H. pylori infection in adults (>17 years of age). For children and adolescents, refer to Helicobacter pylori Breath Test, Pediatric.


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