MYD88 Mutation Detection by NGS


Sunquest Code:MYD88CoPath Code:MYD88
Epic Code:LAB8071Epic Name:MYD88 Mutation Detection by NGS
Synonyms:L265P; Lymphoplasmacytic Lymphoma
Methodology:Next generation sequencing
Turnaround Time:Performed Mon-Fri; results are reported within 10-14 days.


Collection Instructions

Specimen:Blood, bone marrow
Optimal Volume:10 mL blood; 3 mL bone marrow
Minimum\Peds Volume:3 mL blood, 1 mL bone marrow
Container:Yellow (ACD, Solution A) tube available from laboratory (Purple (EDTA))
Collection Instructions:Bone marrow clot acceptable for testing
Causes for Rejection:Whole blood: frozen or clotted specimen, incorrect anticoagulant, specimen more than 5 days old. All testing will be cancelled if engraftment testing is 100% donor engrafted in consultation with clinician.
Shared blood or bone marrow samples will not be accepted unless sent to Molecular first. Contamination will occur on automated hematology analyzers.
The diagnostic sample for hematology panels (not including MPN) requires at least 20% blasts to perform testing. Follow up samples for the hematology panels will be tested for all the gene(s) positive in the diagnostic sample.


Processing and Shipping

Specimen Processing:Do not process. Store at room temperature.
Shipping Instructions:Ship at room temperature. Do not refrigerate or freeze.
Stability:Whole blood samples are stable for 5 days at room temperature. Do not refrigerate or freeze.
Test Performed at or Referral Lab Molecular Diagnostics  (UMMC-East Bank)


Interpretive

Reference Range:See interpretive report.


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