Platelet Associated Immunoglobulins, Qualitative


Sunquest Code:PAIG  
Epic Code:LAB3657Epic Name:Platelet Associated Immunoglobulin
Synonyms:Platelet Associated IgG; Platelet Associated Antibody; Direct Platelet Associated Antibody; Direct Platelet Antibody; Direct Platelet Antibody Screen
Methodology:Enzyme-linked immunosorbent assay
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri before 10 am; results are reported within 5 days.
Special Instructions:Provide diagnosis, platelet count, and transfusion history on request form. If a UMMC-East patient is suspected to be refractory to platelet transfusions, contact the Blood Bank at 612-273-5367. To expediate delivery of specimen to American Red Cross - samples will be shipped out by Blood Bank.
Associated Links:

ARC Request Form for Submitting Samples



Collection Instructions

Specimen:Blood
Optimal Volume:See Collection Instructions.
Container:Purple (EDTA)
Collection Instructions:Specimen volume is dependent on the patient's platelet count:
  • >100.000 is 16 mL
  • 60,000-100,000 is 25 mL
  • 25,000-59,999 is 40 mL
  • Testing is not performed if the platelet count is less than 25,000

See ARC Request Form in Associated Links for further information.  
Causes for Rejection:Hemolysis.


Processing and Shipping

Specimen Processing:Whole blood. Do not process. Store at room temperature.
Shipping Instructions:Ship at room temperature. Must arrive at Red Cross National Referene Lab within 48 hours of collection. Hours of receipt for Red Cross National Reference Lab: M-Th 7A-4P; Fri 7A-12 Noon. Must include completed National Referene Laboratory for Specialized Testing Request Form (or ARC Connect request). Send directly to National Reference Lab, do not route to St. Paul ARC or Specimen Management. When sending sample by FedEx Express the day before, it should arrive before 12 Noon the next day. If needed, Use FedEx Priority Overnight, which should arrive before 10:30A the next day.
Stability:Must arrive within 48 hours.
Test Performed at or Referral Lab Lab Sendouts  (Blood Services Penn-Jersey Region Musser Blood Center)
Referral Lab number:PAIG


Interpretive

Reference Range:Reported as positive or negative.
Use:Differentiates immune mediated thrombocytopenia from other thrombocytopenic disorders. Increased levels of platelet associated IgG and IgM are detected in 92% and 42% respectively, in patients with autoimmune thrombocytopenic purpura.


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