Group B Strep PCR, Fairview Range

Sunquest Code:GBSPCR  
Epic Code:LAB3495Epic Name:Group B Strep PCR
Synonyms:GBS; GBSPCR; Beta Strep; Streptococcus; Genital; B Streptococcus
Methodology:Automated polymerase chain reaction (PCR)
Turnaround Time:Performed 7 days a week; results are reported within 1 day.

Collection Instructions

Specimen:Females: Vaginal or vaginal/rectal swab
Container:CoPan Dual Swab
Collection Instructions:Wipe away excessive vaginal excretions from the mucosa. Insert the same swab beyond the anal sphincter and rotate. Replace the swab in its container and label with patient's identification.
Contraindications:Patients who have used systemic or topical (vaginal) antibiotic treatment in the week prior, as well as patients diagnosed with placenta previa, whould not be tested with the Xpert GBS LB assay.

Processing and Shipping

Specimen Processing:Store swab at refrigerated temperature for up to 6 days. Swabs stored at room temperature are stable for 48 hours.
Shipping Instructions:Ship swab at refrigerated temperature.
Test Performed at or Referral Lab Microbiology  (Fairview Range - FRMC)


Reference Range:Negative for group B streptococcus by PCR.
Use:Detect  Group B streptococcus in the genetial tracts of expectant mothers. Identify infants at risk for infection and guide intrapartum administration of antibiotics. One aproach has been adopted to reduce this disease: Guidelines advicate all pregnant women have a vaginal/rectal screening test for GBS between35 and 37 weeks gestation.

Screening Based Strategy
  • Perform vaginal/rectal screen at 35-37 weeks.
  • If positive, admiister intrapatrum antibiotic
  • If results unknown (delivery <37 weeks) administer inrapartum antibiotics
  • If results unknown (delivery ≥ 37 weeks) refer to risk-based strategy
  • If negative, do not administer intrapartum antibiotics

*Concensus Guidelines for the Prevention of Perinatal Group B Streptococcal Disease (from the Centers for Disease Control and Prevention), Atlanta, GA.

Susceptibility testing is automatically initiated on all specimens that are positive for group B streptococcus by PCR.

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