Heparin Unfractionated Anti Xa Level


Sunquest Code:AAUFH  
Epic Code:LAB8132Epic Name:Heparin Unfractionated Anti Xa Level
Synonyms:Heparin Xa; Heparin Level; Anti 10A; Anti Xa; UFH Anti 10A Level; UFH Anti Xa Level
Methodology:Chromogenic (synthetic substrate) activity assay
Turnaround Time:Performed and reported 24 hours/day
Associated Links:

Specimen Collection and Processing for Coagulation Specimens



Collection Instructions

Specimen:Blood
Optimal Volume:2.7 mL (in 3 mL tube) - filled to fill line on the tube.
Minimum\Peds Volume:1.8 mL (in 2 mL tube) - filled to fill line on the tube.
Container:Blue Na Citrate, 3.2% - fill to fill line on tube
Collection Instructions:If the patient's hematocrit is >55%, contact laboratory to obtain a special tube. If using a butterfly needle, a waste tube must be collected before the blue top tube.
After Care:If the patient has a coagulation abnormality, apply direct pressure to the puncture site for 10 minutes; apply a pressure dressing. Instruct the patient to leave the bandage on for 12 hours.
Causes for Rejection:Underfilled tubes, overfilled tubes, clotted specimens, specimen collected in 3.8% buffered citrate. Whole blood specimen greater than 2 hours old, or not processed appropriately within 1 hour of collection.


Processing and Shipping

Specimen Processing:Must be processed within 1 hour of collection. See Associated Links for additional processing instructions.
Shipping Instructions:Ship processed plasma on dry ice. Must arrive within 48 hours.
Test Performed at or Referral Lab Coagulation  (Fairview Range - FRMC, UMMC-East Bank, Fairview Lakes - FLMC, Fairview Ridges - FRH, Fairview Northland - FNMC, Fairview Southdale - FSH, UMMC/UMMCH-West Bank, Grand Itasca GICH)


Interpretive

Critical Range:>1.10 IU/mL
Therapeutic Range:If collected 4-6 hours after administration:
0.25-0.50 IU/mL for low intensity dosing;
0.30-0.70 IU/mL for high intensity dosing for DVT and PE.
Use:Estimate the concentration of physiologically active heparin anticoagulant (anti-Factor Xa activity) in plasma.


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