Chlamydia Antibody Panel, IgG and IgM by IFA


    
Epic Code:See C&P OrderEpic Name:IP Lab Panel Chlamydia Antibodies IgG IgM Panel
Order Instructions:Epic SmartGroup order codes: Outpatient: O4046000015 Inpatient: 3046000015 Code orders Chlamydia Antibody Panel, IgG by IFA and Chlamydia Antibody Panel, IgM by IFA
Synonyms:Psittacosis serology
Methodology:Indirect fluorescent antibody
CPT Code:86631, 86632
Test Includes:IgG and IgM testing for C. pneumoniae, C. psittaci, and 9 serotypes of C. trachomatis. The LGV strains of C. trachomatis are not included in this assay.
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-4 days.
Special Instructions:Parallel testing is preferred. Label samples as acute or convalescent.
Compliance:

Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.



Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.5 mL
Container:Red (no gel) (Red or gold (gel))
Causes for Rejection:Hemolyzed or lipemic specimens


Processing and Shipping

Specimen Processing:Separate serum from cells ASAP. Centrifuge and aliquot 1 mL, 0.15 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:65100


Interpretive

Reference Range:

 

IgG titer

C. trachomatis

Less than 1:64=Not detected

C. pneumoniae

Less than 1:64=Not detected

C. psittaci

Less than 1:64=Not detected

Any IgG titer may indicate past exposure to that particular species. When seen, cross-reactive antibody or the presence of non-specifically stimulated chlamydial IgG antibody is typically less than 128. Infection with a particular chlamydial species typically yields antibody titers which are higher than antibody titers to the non-infecting species. IgG titers in recently infected individuals are typically greater than 512.

 

 

IgM titer

C. trachomatis

Less than 1:20=Not detected

C. pneumoniae

Less than 1:20=Not detected

C. psittaci

Less than 1:20=Not detected

IgM response normally occurs 7-14 days after onset of disease. Low levels of IgM may occasionally persist for more than 12 months post-infection or immunization. Residual IgM response may be distinguished from early IgM response to infection by testing sera from patients 2-3 weeks later for changing levels. Chlamydial IgM antibody is very cross-reactive and will often represent titers to multiple species.

 

 



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