DNA Cell Cycle Analysis Ploidy and S-Phase - LG761

Sunquest Code:ARMISC  
Epic Code:LAB4909Epic Name:Send Outs Misc Test
Synonyms:Aneuploidy Analysis; Cell Cycle Analysis; Ploidy Analysis; Tumor Cell DNA Ploidy Analysis; Neoplasm Analysis; FLODNA
Methodology:Flow cytometry
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 3-9 days.
Special Instructions:Indicate specimen source on request form.

This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Collection Instructions

Specimen:Blood, bone marrow, body fluid or tissue
Optimal Volume:5 mL whole blood; 2 mL bone marrow, 100 mL body fluid or 2 blocks of formalin-fixed paraffin embedded tissue
Minimum\Peds Volume:1 mL whole blood or bone marrow, 10 mL body fluid or 1 block of formalin-fixed paraffin embedded tissue
Container:Green (sodium heparin, no gel) (Plastic leakproof container, sterile, Container, Tissue, sterile)
Collection Instructions:

Collect whole blood or bone marrow in green (sodium heparin, no gel) tube. Send specimen in original container and include specimen source on container.


Provide a Wright stained slide with all bone marrow and whole blood specimens along with clinical information and specimen source.


Causes for Rejection:Products of conception. No tumor tissue remaining on block. Specimens fixed in Bouin's solution (picric acid), mercuric chloride containing fixatives (e.g. B5, Zenker's solution) or ethanol-based fixatives containing ethylene glycol, acetic acid or zinc chloride. Clotted or hemolyzed blood or bone marrow. Decalcified specimens. Frozen specimens.

Processing and Shipping

Specimen Processing:Do not process.
Shipping Instructions:Ship overnight at refrigerated temperature. Blood or bone marrow samples must be received within 48 hours of collection.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:95155


Reference Range:By report. Report components include: DNA content, S-phase interpretation and a copy of histogram.
Use:The diagnostic and prognostic importance of tumor DNA content depends on the tumor type and source of tissue. Interpretive information, if available for the tumor type, is included with the DNA histogram.

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