Tissue, Gross and Microscopic Examination

Sunquest Code:SRGPTHCoPath Code:PATH
Epic Code:LAB4613Epic Name:Pathology Exam
Synonyms:Tissue Pathology; Surgical Pathology; Biopsy; Gross and Microscopic Pathology; M Health Reflex Cancer Panels; Fairview Cancer Panels; Lymphoma Workup Surgical Pathology
Test Includes:Bone and/or calcified specimens require demineralization at an additional charge.
Turnaround Time:Performed Mon-Fri, 0800-1600.
Special Instructions:At UMMC, East and West Banks: Same day Rush processing when specimen is received in laboratory by 1200. On weekends and holidays, contact fellow/resident on call through the hospital page operator. Routine results are reported within 1-2 days; tissues requiring special stains and other procedures may take longer. Provide clinical history, surgical findings and exact location, duration and description of each lesion submitted on request form.
Associated Links:

Cancer Panels Algorithm

Collection Instructions

Specimen:Fresh or fixed tissue; Specimens which only require gross examination include: calculi, foreign bodies or intraocular lens. See entity policy for specimens exempt from mandatory pathology examination.
Optimal Volume:Entire intact specimen
Container:See Collection Instructions
Collection Instructions:

If frozen section or special studies (e.g., immunohistochemistry, electron microscopy, tissue culture) are contemplated, contact Surgical Pathology for appropriate technique or fixative. The volume of fixative should be 10-15 times the volume of tissue. The container should be large enough to allow specimen removal after hardening by fixative.


Biopsies taken in Patient Care Units and Clinics:

·          Place specimen in fixative immediately upon removal. 10% neutral buffered formalin is suitable for most purposes. AZF fixative is used for selected lymph nodes. 10% buffered neutral formalin is the fixative of choice for lymph nodes at FSH. A 3 part kit is available for renal biopsies at FSH and FRH.

·          When a special study is contemplated such as enzyme histochemistry, electron microscopy, immunohistochemistry, tissue culture or biochemical determination, contact pathologist on call to identify the appropriate technique and fixative for the procedure. Some specimens for special procedures must be hand delivered immediately to the lab.


Biopsies taken in the Operating Room:

·          Deliver organ or tissue specimens removed during surgery intact and unsectioned to Surgical Pathology Laboratory.

·          When sectioning of the specimen in the Operating Room is deemed necessary, contact Surgical Pathologist, who will perform or oversee sectioning of the specimen.

·          When portions of a resected specimen are required for investigative studies (electron microscopy, tissue culture, immunology research, etc.), the specimen should be delivered first to Surgical Pathology.  The pathologist will, upon request, provide segments of the specimen for special studies.

·          When a culture must be taken from a specimen, it should be performed in the Operating Room where a sterile field exists before delivering the specimen to laboratory.

·          Any large specimen that must be transported in a basin should be covered with a biohazard plastic bag.


Processing and Shipping

Specimen Processing:Store fixed specimens at room temperature.
Shipping Instructions:Ship fixed specimens at room temperature.
Test Performed at or Referral Lab Anatomic Pathology, UMMC/UMCH West Bank  (UMMC-East Bank, Fairview Lakes - FLMC, Fairview Ridges - FRH, Fairview Northland - FNMC, Fairview Southdale - FSH, UMMC/UMMCH-West Bank)


Reference Range:Interpretive report.
Use:Histologic diagnosis of benign, malignant or infectious processes.

Click HERE to Report test errors or omissions.
*If no email program is associated with this computer, please contact:
systemlabguide@fairview.org for TestID: 837"