Bone Marrow Aspirate and Trephine Biopsy, Morphology


Sunquest Code:BMSPHCoPath Code:MARR
Epic Code:LAB6  
Sunquest Code (non-Epic sites):COPATH  
Synonyms:Biopsy, Bone Marrow Aspirate/Trephine; Trephine Biopsy
Methodology:Microscopic
Test Includes:Examination of bone marrow aspirate, trephine biopsy and peripheral blood smears.
Turnaround Time:Preliminary results are available in 24 hours, final results are reported within 48 hours.


Collection Instructions

Specimen:Bone marrow and peripheral blood.
Container:Purple (EDTA), Microscope slides
Collection Instructions:
  • When bone marrow has been processed: Provide 4-8 unstained direct smears, 8 unstained bone marrow concentrate smears and 4-6 unstained peripheral blood smears (prepared from fresh [less than 4 hours after collection] blood.
  • When bone marrow has not been proessed: Provide one 5 mL bone marrow aspirate in EDTA, 4-8 unstained direct aspirate smears, 4-6 unstained peripheral blood smears (prepared from fresh [less than 4 hours after collection] blood, unstained biopsy touch imprints, and bone marrow core (trephine) biopsy submitted in a container of AZF fixative.
   


Processing and Shipping

Specimen Processing:Store at room temperature.
Shipping Instructions:Ship slides in protective slide holder(s) and bone marrow aspirate(s) in a tightly sealed container at room temperature. Bone marrow core (trephine) biopsy submitted in a container of fixative that is tightly sealed must be sent in a separate sample transport bag at room temperature.
Test Performed at or Referral Lab Hematopathology  (UMMC-East Bank, Fairview Lakes - FLMC, Fairview Ridges - FRH, Fairview Northland - FNMC, Fairview Southdale - FSH)


Interpretive

Reference Range:Interpretive report by hematopathologist or pathologist.
Use:Evaluation of patients with suspected disorders of the hematopoietic system including all forms of leukemia, anemia, lymphoma, and myeloma. Also used for investigation of patients with metastatic malignancies. Nonmalignant disorders in which marrow biopsies are appropriate are suspected infectious processes (culture and examine for granulomas) and inherited metabolic disorders.


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