Vitamin A

Abbrev Code:VITAA   
Order Code:LAB580Order Name:Vitamin A
Methodology:High performance liquid chromatography
CPT Codes: 84590 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-4 days.

For tests developed and validated by ARUP (previously referred to as Compliance Statement B, C or D). This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:0.6 mL
Container:Red or gold (gel)
Alternate Containers: Green (lithium heparin, no gel), Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel)
Patient Preparation:Fast overnight (12 hours). Avoid alcohol for 1 day prior to collection.
Causes for Rejection:Whole blood or body fluids other than serum or plasma. Room temperature specimens.

Processing and Shipping

Specimen Processing:Within 1 hour of collection, centrifuge and aliquot 1 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 1 month refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:80525


Reference Range:

Vitamin A (Retinol)

      0-1 mo

      2 mo -12 y:

      13-17 y

      18 y and older


0.18-0.50 mg/L

0.20-0.50 mg/L

0.26-0.70 mg/L

0.30-1.20 mg/L

Retinyl Palmitate, all ages

0.00-0.10 mg/L



Use:Serum retinol is typically maintained until hepatic stores are almost depleted. Values greater than 0.30 mg/L represent adequate liver stores, whereas values less than 0.10 mg/L indicate deficiency. Samples that come in contact with plastic tubing or have been exposed to excessive light may show low results. Vitamin A toxicity occurs when retinol concentration exceeds the capacity of retinol binding protein (RBP). Individuals with compromised renal function can retain RBP and may, therefore, have moderate retinol elevations. Drugs which interfere with vitamin A analysis include probucol (Lorelco). This assay does not measure other Vitamin A metabolites such as retinaldehyde or retinoic acid.

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