Rubella Antibody, IgM
Abbrev Code: | RUIGM | ||
Order Code: | LAB6358 | Order Name: | Rubella IgM |
Synonyms: | German Measles Antibody Titer, IgM | ||
Methodology: | Chemiluminescent immunoassay | ||
CPT Codes: | 86762 x1 | ||
Turnaround Time: | Performed 3x per week; results are reported the next day. |
Collection Instructions
Specimen: | Blood |
Optimal Volume: | 2 mL |
Minimum\Peds Volume: | 0.9 mL |
Container: | Red or gold (gel) Alternate Containers: Red (no gel) |
Causes for Rejection: | Gross hemolysis |
Processing and Shipping
Specimen Processing: | Centrifuge and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 7 days. |
Shipping Instructions: | Ship at refrigerated temperature. |
Stability: | CSF accepted |
Test Performed at or Referral Lab | UM Specialty Core/Prot/Endo (Liaison D) |
Interpretive
Reference Range: |
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Use: | Aid in diagnosis of primary rubella infection in pregnant women and congenital rubella infection in neonates. IgM antibodies become detectable in a few days after the onset of signs and symptoms and reach peak levels in 7-10 days. These antibodies persist, but rapidly diminish in concentration over the next 4-5 weeks until the antibody is no longer clinically detectable. The present of IgM antibody in a single specimen suggests that the patient has recently experienced a rubella infection. In most cases, the infection probably occurred within the preceding 1-3 months. Rubella IgM antibody in a newborn's serum suggests congenital infection since IgM from the mother is not transferred to the infant across the placenta. The infected infant, in contrast to a woman with prenatal rubella, may continue to produce rubella-specific IgM for several months. |
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