Rubella Antibody, IgM
| Sunquest Code: | RUIGM | ||
| Epic Code: | LAB6358 | Epic Name: | Rubella IgM |
| Synonyms: | German Measles Antibody Titer, IgM | ||
| Methodology: | Chemiluminescent immunoassay | ||
| Turnaround Time: | Performed Mon-Fri; results reported the same day. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.9 mL |
| Container: | Red or gold (gel) [Alternate Containers: Red (no gel)] |
| Causes for Rejection: | Gross hemolysis |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 7 days. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | CSF accepted |
| Test Performed at or Referral Lab | Specialty Core (UMMC-East Bank) |
Interpretive
| Reference Range: |
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| Use: | Aid in diagnosis of primary rubella infection in pregnant women and congenital rubella infection in neonates. IgM antibodies become detectable in a few days after the onset of signs and symptoms and reach peak levels in 7-10 days. These antibodies persist, but rapidly diminish in concentration over the next 4-5 weeks until the antibody is no longer clinically detectable. The present of IgM antibody in a single specimen suggests that the patient has recently experienced a rubella infection. In most cases, the infection probably occurred within the preceding 1-3 months. Rubella IgM antibody in a newborn's serum suggests congenital infection since IgM from the mother is not transferred to the infant across the placenta. The infected infant, in contrast to a woman with prenatal rubella, may continue to produce rubella-specific IgM for several months. | ||||||||
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