Alport Antigen
| Abbrev Code: | Surg Path Ex | ||
| Order Code: | LAB4613 | Order Name: | Alport Antigen |
| Order Instructions: | Test should be ordered as COPATH: ALP-K (for kidney tissue); ALP-S (for skin) | ||
| Synonyms: | Familial Nephritis; Hereditary Nephritis; Nephritis, Hereditary | ||
| Methodology: | Direct immunofluorescence | ||
| CPT Codes: | 88346 x1, 88350 x1 | ||
| Test Includes: | Direct immunofluorescence for alpha chains of Type IV collagen. | ||
| Turnaround Time: | Performed weekly; results are reported within 2 days. | ||
Collection Instructions
| Specimen: | Tissue (kidney, skin) |
| Container: | Container, Tissue, sterile Alternate Containers: Plastic leakproof container, sterile |
| Collection Instructions: | Freeze tissue in 2-methylbutane (isopentane) and liquid nitrogen. Do not allow specimen to thaw; keep frozen. Alternatively, preserve tissue with Michel's or Zeus fixative at room temperature. Deliver specimen to UMMC West Bank Pathology Lab, M351, 3rd floor East Bldg. Call laboratory at 612-273-4022, option 4 for instructions. |
| Causes for Rejection: | Specimen in formalin or Zenker's fixative; improper freezing. |
Processing and Shipping
| Specimen Processing: | Store frozen tissue on dry ice or -70C freezer. Store tissue preserved with Michel's or Zeus fixative at room temperature. |
| Shipping Instructions: | Ship frozen tissue on dry ice. Ship Zeus or Michel's fixed tissue at room temperature. Must arrive within 24 hours. Ship overnight express Mon-Thurs only. Do not ship on Fridays. |
| Test Performed at or Referral Lab | Anatomic Pathology, West Bank |
Interpretive
| Use: | To aid in the diagnosis of Alport's syndrome. |
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