Alport Antigen

Abbrev Code:Surg Path Ex   
Order Code:LAB4613Order Name:Alport Antigen
Order Instructions:Test should be ordered as COPATH: ALP-K (for kidney tissue); ALP-S (for skin)
Synonyms:Familial Nephritis; Hereditary Nephritis; Nephritis, Hereditary
Methodology:Direct immunofluorescence
CPT Codes: 88346 x1, 88350 x1
Test Includes:Direct immunofluorescence for alpha chains of Type IV collagen.
Turnaround Time:Performed weekly; results are reported within 2 days.

Collection Instructions

Specimen:Tissue (kidney, skin)
Container:Container, Tissue, sterile
Alternate Containers: Plastic leakproof container, sterile
Collection Instructions:Freeze tissue in 2-methylbutane (isopentane) and liquid nitrogen. Do not allow specimen to thaw; keep frozen. Alternatively, preserve tissue with Michel's or Zeus fixative at room temperature. Deliver specimen to UMMC West Bank Pathology Lab, M351, 3rd floor East Bldg. Call laboratory at 612-273-4022, option 4 for instructions.
Causes for Rejection:Specimen in formalin or Zenker's fixative; improper freezing.

Processing and Shipping

Specimen Processing:Store frozen tissue on dry ice or -70C freezer. Store tissue preserved with Michel's or Zeus fixative at room temperature.
Shipping Instructions:Ship frozen tissue on dry ice. Ship Zeus or Michel's fixed tissue at room temperature. Must arrive within 24 hours. Ship overnight express Mon-Thurs only. Do not ship on Fridays.
Test Performed at or Referral Lab Anatomic Pathology, West Bank 


Use:To aid in the diagnosis of Alport's syndrome.

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