Anaplasma Phagocytophilum (HGA) Antibodies, IgG and IgM


Abbrev Code:APHAGM   
Order Code:LAB3288Order Name:Anaplasma Phagocytoph Antibody IGG IGM
Synonyms:Human Granulocytic Ehrlichiosis; Tick Borne Diseases; HGE; Ehrlichia equii
Methodology:Indirect fluorescent antibody, semi-quantitative
CPT Codes: 86666 x2
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 1-5 days.
Compliance:

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.


Collection Instructions

Specimen:Blood
Optimal Volume:1 mL
Minimum\Peds Volume:0.6 mL
Container:Red or gold (gel)
Alternate Containers: Red (no gel)
Causes for Rejection:Hemolyzed, lipemic, icteric, heat inactivated, bacterially contaminated or turbid specimens.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 0.5 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:0097303


Interpretive

Reference Range:

Anaplasma phagocytophilum (HGA) Antibody IgG

Less than 1:80: No significant level of IgG antibodies to A. phagocytophilum detected.

Greater than or equal to 1:80: Suggestive of a recent or past infection with A. phagocytophilum

Anaplasma phagocytophilum (HGA) Antibody IgM

Less than 1:16: No significant level of IgM antibodies to A. phagocytophilum detected.

Greater than or equal to 1:16: Suggestive of a recent or past infection with A. phagocytophilum

 

 

Use:

Human ehrlichiosis is a tick-borne zoonotic infection caused by rickettsial-like agents. Two forms, human monocytic ehrlichiosis (HME) and human granulocytic ehrlichiosis (HGE) have been described. HME is often referred to as “spotless” or rashless Rocky Mountain spotted fever. The causative agent of HME has been identified as Ehrlichia chaffeensis. The two infections are clinically indistinguishable.

 



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