C1 Esterase Inhibitor


Abbrev Code:C1INH   
Order Code:LAB3345Order Name:C1 Esterase Inhibitor Total
Synonyms:Complement 1 Esterase Inhibitor, Quantitation
Methodology:Turbidmetric
CPT Codes: 86160 x1, 86160 x12
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-4 days.
Compliance:

This test uses an in vitro diagnostic (IVD) that has been cleared or approved by the FDA.



Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:1.2 mL
Container:Red or gold (gel)
Alternate Containers: Red (no gel)
Causes for Rejection:Room temperature specimen; grossly hemolyzed or lipemic specimen.


Processing and Shipping

Specimen Processing:Separate serum from cells ASAP. Centrifuge and aliquot 1 mL, 0.5 mL minimum. Store refrigerated.
Shipping Instructions:Ship refrigerated.
Stability:Unacceptable at room temperature; 14 days refrigerated; 1 month frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:50140


Interpretive

Reference Range:21-38 mg/dL
Use:A deficiency of functionally active component of C1-INH may lead to life-threatening angioedema. Two major forms of C1-INH deficiency have been reported: the congenital form and the acquired form. In the congenital form, termed hereditary angioedema (HAE), there is a quantitative deficiency in C-1-esterase inhibitor.


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