C1 Esterase Inhibitor
| Abbrev Code: | C1INH | ||
| Order Code: | LAB3345 | Order Name: | C1 Esterase Inhibitor Total |
| Synonyms: | Complement 1 Esterase Inhibitor, Quantitation | ||
| Methodology: | Turbidmetric | ||
| CPT Codes: | 86160 x1, 86160 x12 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-4 days. | ||
| Compliance: | This test uses an in vitro diagnostic (IVD) that has been cleared or approved by the FDA. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 1.2 mL |
| Container: | Red or gold (gel) Alternate Containers: Red (no gel) |
| Causes for Rejection: | Room temperature specimen; grossly hemolyzed or lipemic specimen. |
Processing and Shipping
| Specimen Processing: | Separate serum from cells ASAP. Centrifuge and aliquot 1 mL, 0.5 mL minimum. Store refrigerated. |
| Shipping Instructions: | Ship refrigerated. |
| Stability: | Unacceptable at room temperature; 14 days refrigerated; 1 month frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 50140 |
Interpretive
| Reference Range: | 21-38 mg/dL |
| Use: | A deficiency of functionally active component of C1-INH may lead to life-threatening angioedema. Two major forms of C1-INH deficiency have been reported: the congenital form and the acquired form. In the congenital form, termed hereditary angioedema (HAE), there is a quantitative deficiency in C-1-esterase inhibitor. |
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