C1 Esterase Inhibitor
| Sunquest Code: | C1INH | ||
| Epic Code: | LAB3345 | Epic Name: | C1 Esterase Inhibitor Total |
| Synonyms: | Complement 1 Esterase Inhibitor, Quantitation | ||
| Methodology: | Nephelometry | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-4 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 1.0 mL |
| Container: | Red or gold (gel) (Red (no gel)) |
Processing and Shipping
| Specimen Processing: | Separate serum from cells ASAP. Centrifuge and aliquot 1 mL, 0.4 mL minimum. Freeze within 2 hours. Separate specimens must be submitted when multiple tests are ordered. |
| Shipping Instructions: | Ship on dry ice. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 50140 |
Interpretive
| Reference Range: | 21-39 mg/dL |
| Use: | A deficiency of functionally active component of C1-INH may lead to life-threatening angioedema. Two major forms of C1-INH deficiency have been reported: the congenital form and the acquired form. In the congenital form, termed hereditary angioedema (HAE), there is a quantitative deficiency in C-1-esterase inhibitor. |
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