Carcinoembryonic Antigen (CEA)


Abbrev Code:CEA   
Order Code:LAB57Order Name:CEA
Methodology:Roche: Immunoassay
CPT Codes: 82378 x1, 82378 x1
Turnaround Time:Performed and reported 24 hours/day.
Associated Links:

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Collection Instructions

Specimen:Blood
Optimal Volume:2.5 mL
Minimum\Peds Volume:1.4 mL
Container:Green (lithium heparin, gel)
Alternate Containers: Green (lithium heparin) on ICE, Red (no gel), Red or gold (gel)
Causes for Rejection:Serum not separated from cells within 8 hours after collection. Gross hemolysis.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1.25 mL, 0.6 mL minimum. Store in refrigerator or freeze.
Shipping Instructions:Ship at refrigerated temperature. Alternatively, ship on dry ice.
Stability:8 hours at room temperature; 48 hours refrigerated; indefinitely frozen.
Test Performed at or Referral Lab Chemistry  (Roche-UMMC East)


Interpretive

Reference Range:
Age Non-Smokers
(ng/mL)
Smokers
(ng/mL)
20-69 y 0-3.8 0-5.5
40-69 y 0-5.0 0-6/5
 
Use:Monitoring of patients with carcinoma of the colon, pancreas and breast neoplasm. At least two progressive elevations of CEA at one month intervals may herald tumor recurrence 3-36 months before clinical evidence of metastasis. A shallow rise may signal local recurrence, while a large rise in values may indicate hepatic metastasis. CEA levels are increased in smokers.


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