Complement Component C2
| Sunquest Code: | C2 | ||
| Epic Code: | LAB153 | Epic Name: | Complement C2 |
| Synonyms: | C2 | ||
| Methodology: | Radial immunodiffusion | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported in 5-9 days. | ||
| Compliance: | This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.8 mL |
| Container: | Red or gold (gel) (Red (no gel)) |
| Causes for Rejection: | Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles. Specimens left to clot at refrigerated temperature. |
Processing and Shipping
| Specimen Processing: | Allow specimen to clot 60 minutes at room temperature. Centrifuge and aliquot 1 mL, 0.3 mL minimum. Requires separate aliquot. Freeze within 2 hours. |
| Shipping Instructions: | Ship on dry ice. |
| Stability: | After separation from cells: 2 hours at room temperature; 2 weeks frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 50148 |
Interpretive
| Reference Range: | 1.6-4.0 mg/mL Decreased C2 levels may be associated with increased susceptibility to infection (especially pneumococcal infections), systemic lupus erythematous-like disease, rashes, arthritis, nephritis, and with C1-Esterase deficiency. Increased C2 levels are associated with the acute phase response. |
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