Alpha-2-Antiplasmin Chromogenic


Abbrev Code:A2AP   
Order Code:LAB6333Order Name:Alpha-2-Antiplasmin Activity
Synonyms:Anti-Plasmin Functional Assay; Alpha-2-Antiplasmin Activity; Antiplasmin
Methodology:Chromogenic assay
CPT Codes: 85410 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; testing performed on Thursdays;  results are reported within 1-8 days.
Associated Links:

Specimen Collection and Processing for Coagulation Specimens



Collection Instructions

Specimen:Blood
Optimal Volume:2.7 mL (in 3 mL tube) - filled to fill line on the tube.
Minimum\Peds Volume:1.8 mL (in 2 mL tube) - filled to fill line on the tube.
Container:Blue Na Citrate, 3.2% - fill to fill line on tube
Collection Instructions:See link to Specimen Collection and Processing for Coagulation Specimens.
Causes for Rejection:Underfilled tubes, nonfrozen or hemolyzed specimens.


Processing and Shipping

Specimen Processing:Centrifuge the specimen at 1700 x g for 15 minutes (or at a speed and time required to consistently produce platelet-poor plasma - platelet count less than 10,000/uL). Aliquot within 4 hours of collection 1 mL; 0.5 mL minimum of platelet-poor plasma. Store in freezer.
Shipping Instructions:Ship frozen.
Stability:Frozen at -20ºC for 3 months; at -70ºC for 6 months
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:98727


Interpretive

Reference Range:
A2AP Activity %
1-4d 55-115
5-29d 70-130
30-89d 76-124
90-179d 76-140
180-364d 83-139
1-5y 93-117
6y 89-110
7-9y 88-147
10-11y 90-144
12-13y 87-142
14-15y 83-136
16-17y 77-134
18 & older 82-133
Use:Alpha-2 Antiplasmin is a specific inhibitor of Plasmin. A deficiency may result in a bleeding tendency. Homozygous deficiency may cause severe bleeding. Elevated levels may cause thrombosis.


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