Alpha-2-Antiplasmin Chromogenic
| Abbrev Code: | A2AP | ||
| Order Code: | LAB6333 | Order Name: | Alpha-2-Antiplasmin Activity |
| Synonyms: | Anti-Plasmin Functional Assay; Alpha-2-Antiplasmin Activity; Antiplasmin | ||
| Methodology: | Chromogenic assay | ||
| CPT Codes: | 85410 x1 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; testing performed on Thursdays; results are reported within 1-8 days. | ||
| Associated Links: | Specimen Collection and Processing for Coagulation Specimens |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.7 mL (in 3 mL tube) - filled to fill line on the tube. |
| Minimum\Peds Volume: | 1.8 mL (in 2 mL tube) - filled to fill line on the tube. |
| Container: | Blue Na Citrate, 3.2% - fill to fill line on tube |
| Collection Instructions: | See link to Specimen Collection and Processing for Coagulation Specimens. |
| Causes for Rejection: | Underfilled tubes, nonfrozen or hemolyzed specimens. |
Processing and Shipping
| Specimen Processing: | Centrifuge the specimen at 1700 x g for 15 minutes (or at a speed and time required to consistently produce platelet-poor plasma - platelet count less than 10,000/uL). Aliquot within 4 hours of collection 1 mL; 0.5 mL minimum of platelet-poor plasma. Store in freezer. |
| Shipping Instructions: | Ship frozen. |
| Stability: | Frozen at -20ºC for 3 months; at -70ºC for 6 months |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 98727 |
Interpretive
| Reference Range: |
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| Use: | Alpha-2 Antiplasmin is a specific inhibitor of Plasmin. A deficiency may result in a bleeding tendency. Homozygous deficiency may cause severe bleeding. Elevated levels may cause thrombosis. |
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