Fibrinogen Antigen

Abbrev Code:FIBAG   
Order Code:LAB6052Order Name:Fibrinogen Antigen
Synonyms:Factor 1 Antigen
Methodology:Radial immunodiffusion
CPT Codes: 85385 x1
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 3-5 days.

Collection Instructions

Optimal Volume:2.7 mL (in 3 mL tube) - filled to fill line on the tube.
Minimum\Peds Volume:1.8 mL (in 2 mL tube) - filled to fill line on the tube.
Container:Blue Na Citrate, 3.2% - fill to fill line on tube
Causes for Rejection:Underfilled tube, hemolyzed specimens

Processing and Shipping

Specimen Processing:Centrifuge and aliquot 2 mL, 1 mL minimum. Store in freezer.
Shipping Instructions:Ship on dry ice.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:30135


Reference Range:149-353 mg/dL
Use:Fibrinogen abnormalities can be either quantitative (hypofibrinogenemia), qualitative (dysfibrinogenemia) or both. Patients can exhibit bleeding tendencies (25% of cases), pregnancy loss, thrombotic complications (20% of cases), difficulties in wound healing, or no symptoms (53% of cases). The fibrinogen antigen will detect the quantity of the molecule only. The Clauss Fibrinogen assay will detect the level of fibrinogen activity. A discrepancy between the two tests is indicative of dysfibrinogenemia. Therefore, the Fibrinogen Antigen is usually assayed if the Clauss Fibrinogen is low.

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