Fibrinogen Antigen
| Abbrev Code: | FIBAG | ||
| Order Code: | LAB6052 | Order Name: | Fibrinogen Antigen |
| Synonyms: | Factor 1 Antigen | ||
| Methodology: | Radial immunodiffusion | ||
| CPT Codes: | 85385 x1 | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Mon-Sat; results are reported within 3-5 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.7 mL (in 3 mL tube) - filled to fill line on the tube. |
| Minimum\Peds Volume: | 1.8 mL (in 2 mL tube) - filled to fill line on the tube. |
| Container: | Blue Na Citrate, 3.2% - fill to fill line on tube |
| Causes for Rejection: | Underfilled tube, hemolyzed specimens |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 2 mL, 1 mL minimum. Store in freezer. |
| Shipping Instructions: | Ship on dry ice. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 30135 |
Interpretive
| Reference Range: | 149-353 mg/dL |
| Use: | Fibrinogen abnormalities can be either quantitative (hypofibrinogenemia), qualitative (dysfibrinogenemia) or both. Patients can exhibit bleeding tendencies (25% of cases), pregnancy loss, thrombotic complications (20% of cases), difficulties in wound healing, or no symptoms (53% of cases). The fibrinogen antigen will detect the quantity of the molecule only. The Clauss Fibrinogen assay will detect the level of fibrinogen activity. A discrepancy between the two tests is indicative of dysfibrinogenemia. Therefore, the Fibrinogen Antigen is usually assayed if the Clauss Fibrinogen is low. |
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