Ristocetin Induced Platelet Aggregation

Abbrev Code:RAG   
Order Code:LAB3170Order Name:Ristocetin Induced Platelet Aggregation
Synonyms:Quantitative Ristocetin Aggregation; Platelet Function Tests; RIPA
Methodology:Aggregation of patient's platelets using Ristocetin at various concentrations on a Chronolog Platelet Aggregometer.
CPT Codes: 85576 x1, 85576 x1
Special Instructions:The patient must be on site for testing. Call lab (612-273-4797) to schedule.

Collection Instructions

Collection Instructions:Performed by Coagulation Laboratory staff.

Processing and Shipping

Test Performed at or Referral Lab UM Special Coag (K)  (UMMC East Bank)


Reference Range:Interpretive report by Coagulation Laboratory physician.
Use:To differentiate von Willebrand subtypes 2A from 2B. Type 2A aggregates with only normal or high concentrations of Ristocetin (normal to HYPOresponsive). Type 2B aggregates with even low concentrations of Ristocetin (HYPERresponsive). Type 2B patients should not be treated with DDAVP. They may have a severe drop in their platelet count. This test is also part of a Platelet Aggregation workup.

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