Cyanide, Whole Blood


Abbrev Code:CYAN   
Order Code:LAB1205Order Name:Cyanide, Whole Blood
Order Instructions:Do not order if patient is on nitroprusside.
Methodology:High performance liquid chromatography with fluorescence detection
CPT Codes: 82600 x1, 82600 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 5 days.
Special Instructions:Studies have shown that cyanide has variable instability in biological specimens, and is particularly unstable in some postmortem specimens. The loss of cyanide can be minimized by shipping the sample to the laboratory for analysis as soon as possible, preferably using refrigerated or frozen transportation and preservation using sodium fluoride/potassium oxalate (grey top tube). The potential for increases in cyanide concentrations, although rare, have been demonstrated and may be due to microbial action. Preservation with sodium fluoride may reduce this possibility.
Compliance:

Performed by a non-ARUP laboratory.



Collection Instructions

Specimen:Whole Blood
Optimal Volume:1 mL
Minimum\Peds Volume:0.4 mL
Container:Gray (sodium fluoride + potassium oxalate)
Causes for Rejection:Hemolysis


Processing and Shipping

Specimen Processing:Do not centrifuge. Requires 1 mL, 0.4 mL minimum, whole blood in collection tube. Test is not performed at ARUP. Separate specimens must be submitted when multiple tests are ordered. Store in refrigerator (preferred) or freezer.
Shipping Instructions:Ship at refrigerated temperature.
Stability:1 week refrigerated; 3 months frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:3003039


Interpretive

Use:Used to monitor cyanide exposure.


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