Doxepin and Desmethydoxepin

Sunquest Code:XMISC  
Epic Code:LAB4909Epic Name:Doxepin and Desmethydoxepin
Synonyms:Adapin; Sinequan
Methodology:Liquid chromatography/Tandem mass spectrometry
Test Includes:Doxepin and its metabolite N-desmethyldoxepin (nordoxepin)
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 3 days.

Collection Instructions

Optimal Volume:4 mL
Minimum\Peds Volume:1.2 mL
Container:Red (no gel)
[Alternate Containers: Green (lithium heparin, no gel), Green (sodium heparin, no gel)]
Collection Instructions:With patient at steady-state level, collect sample immediately prior to next dose (trough).

Processing and Shipping

Specimen Processing:Centrifuge and aliquot 2 mL, 0.5 mL minimum. Store at room temperature.
Shipping Instructions:Ship at room temperature.
Stability:Up to 3 days at room temperature. For longer storage, refrigerate or freeze.
Test Performed at or Referral Lab Lab Sendouts  (MedTox)
Referral Lab number:45


Critical Range:Greater than 500 ng/mL
Reference Range:Doxepin and metabolite: 50-150 ng/mL
Use:Monitor therapeutic drug levels and assess toxicity.

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