Doxepin and Desmethyldoxepin
| Abbrev Code: | XMISC | ||
| Order Code: | LAB4909 | Order Name: | Laboratory Miscellaneous Order |
| Synonyms: | Adapin; Sinequan | ||
| Methodology: | Liquid chromatography/Tandem mass spectrometry | ||
| CPT Codes: | 80335 x1 | ||
| Test Includes: | Doxepin and its metabolite N-desmethyldoxepin (nordoxepin) | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Fri; results are reported within 3 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 4 mL |
| Minimum\Peds Volume: | 1.2 mL |
| Container: | Red (no gel) Alternate Containers: Green (lithium heparin, no gel), Green (sodium heparin, no gel) |
| Collection Instructions: | With patient at steady-state level, collect sample immediately prior to next dose (trough). |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 2 mL, 0.5 mL minimum. Store at room temperature. |
| Shipping Instructions: | Ship at room temperature. |
| Stability: | Up to 3 days at room temperature. For longer storage, refrigerate or freeze. |
| Test Performed at or Referral Lab | Lab Sendouts (MedTox) |
| Referral Lab number: | 45 |
Interpretive
| Critical Range: | Greater than 500 ng/mL |
| Reference Range: | Doxepin and metabolite: 50-150 ng/mL |
| Use: | Monitor therapeutic drug levels and assess toxicity. |
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