Gabapentin Level


Abbrev Code:GABA   
Order Code:LAB1150Order Name:Gabapentin Level
Synonyms:Neurontin; Gabarone
Methodology:Quantitative liquid chromatography/Tandem mass spectrometry
CPT Codes: 80171 x1, 80171 x1
Turnaround Time:Specimens are sent to the reference laboratory Mon, Wed-Sat; results are reported within 1-4 days.
Compliance:

This test uses a manufacturer labeled Analyte Specific Reagent (ASR) as the reagent providing the specificity of the assay. The test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.



Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.6 mL
Container:Red (no gel)
Alternate Containers: Purple (EDTA)
Collection Instructions:Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Causes for Rejection:Whole blood. Gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution).


Processing and Shipping

Specimen Processing:Centrifuge and separate from cells within 2 hours of collection. Aliquot 1 mL, 0.2 mL minimum. Store at refrigerated temperature.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 1 month at room temperature or refrigerated; 2 months frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:0090057


Interpretive

Critical Range:Toxic range is not well established.
Therapeutic Range:2-20 μg/mL
Use:Optimize drug therapy and monitor patient adherence. Pharmacokinetics of gabapentin vary widely among patients, particularly those with compromised renal function. Adverse effects may include somnolence, dizziness ataxia and fatigue.


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