Mephobarbital
| Abbrev Code: | XMISC | ||
| Order Code: | LAB4909 | Order Name: | Mephobarbital |
| Synonyms: | Mebaral | ||
| Methodology: | Liquid chromatography/Tandem mass spectrometry | ||
| CPT Codes: | 80345 x1 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Fri; results are reported within 3 days. | ||
| Special Instructions: | Rapidly metabolized to phenobarbital; therefore, routine requests will be quantitated as phenobarbital only. Contact the laboratory if a separate mephobarbital result is needed. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 4 mL |
| Minimum\Peds Volume: | 1.2 mL |
| Container: | Red (no gel) Alternate Containers: Green (lithium heparin, no gel), Green (sodium heparin, no gel) |
| Collection Instructions: | Usual sampling time is immediately prior to next dose (trough). |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 2 mL, 0.6 mL minimum. Store at room temperature. |
| Shipping Instructions: | Ship at room temperature. For storage beyond three days, specimen should be refrigerated or frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (MedTox) |
| Referral Lab number: | 69 |
Interpretive
| Critical Range: | 20 ug/mL or greater |
| Reference Range: | 0.8-2.0 ug/mL Expected mephobarbital concentrations are 0.8-2.0 ug/mL or 2-5% of the phenobarbital (metabolite) concentrations. |
| Use: | Therapeutic monitoring and assess toxicity. |
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