Vancomycin


Sunquest Code:VANC  
Epic Code:LAB3870Epic Name:Vancomycin
Methodology:Turbidmetric rate
Grand Itasca: Homogenous enzyme immunoassay
SJO/SJN: Chemiluminescent microparticle immunoassay (CMIA)
Turnaround Time:Performed and reported 24 hours/day.


Collection Instructions

Specimen:Blood
Optimal Volume:2.5 mL
Minimum\Peds Volume:0.6 mL; pediatric patients only: 0.4 mL in green (lithium heparin, no gel)
Container:Red (no gel), St Johns/St Joseph/Woodwinds-Green (lithium heparin, no gel)
[Alternate Containers: Green (lithium heparin, no gel), St Johns/St Joseph/Woodwinds - Red (no gel)]
Collection Instructions:Trough levels: Collect immediately prior to next dose. Peak levels: collect 2 hours after the end of IV infusion; 3-4 hours if decreased renal function.
Causes for Rejection:Collection in a gel tube.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot within 2 hours of collection 1.25 mL, 0.2 mL minimum (adult) 0.1 mL minimum (peds). Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature to arrive within 24 hours. Alternatively, ship on dry ice.
Stability:Comment last dose information; include peak and trough comments.
Test Performed at or Referral Lab Chemistry  (Range, UMMC-East Bank, Lakes, Ridges, Northland, Southdale, UMMC/UMMCH-West Bank, Grand Itasca, St. Joseph's, St. John's, Woodwinds)


Interpretive

Critical Range:Greater than 25 mg/L
Therapeutic Range:Traditional dosing: Trough: 8-20 mg/L; Peak: 20-50 mg/L
Use:Monitor therapeutic drug level. Half-life is 4-10 h (adult); 2-3 h (child); 6-10 h (neonate).


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