Vancomycin
Abbrev Code: | VANC | ||
Order Code: | LAB3870 | Order Name: | Vancomycin |
Methodology: | Roche: Kinetic interaction of microparticles in a solution (KIMS)
Woodwinds: Chemiluminescent microparticle immunoassay (CMIA) |
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CPT Codes: | 80202 x1, 80202 x | ||
Turnaround Time: | Performed and reported 24 hours/day. | ||
Associated Links: |
Collection Instructions
Specimen: | Blood |
Optimal Volume: | 2.5 mL |
Minimum\Peds Volume: | 0.6 mL; pediatric patients only: 0.4 mL |
Collection Instructions: | Chemistry Tests Containers Chart
Trough levels: Collect immediately prior to next dose. Peak levels: collect 2 hours after the end of IV infusion; 3-4 hours if decreased renal function. |
Causes for Rejection: | Collection in a gel tube. |
Processing and Shipping
Specimen Processing: | Centrifuge and aliquot within 2 hours of collection 1.25 mL, 0.2 mL minimum (adult) 0.1 mL minimum (peds). Store in refrigerator. |
Shipping Instructions: | Ship at refrigerated temperature. |
Stability: | Roche: 48 hours at room temperature; 14 days refrigerated; 12 months frozen. Can be frozen and thawed up to 5 times. |
Test Performed at or Referral Lab | Chemistry (Roche-Grand Itasca, Roche-Lakes, Roche-Northland, Roche-Range, Roche-Ridges, Roche-Southdale, Roche-St. John's, Roche-UMMC East, Woodwinds) |
Interpretive
Critical Range: | Roche: Greater than 25 ug/mL
Other sites: Greater than 25 mg/L |
Therapeutic Range: | Roche: Trough: 10-15 ug/mL; Peak 20-40 ug/mL
All others: Trough: 8-20 mg/L; Peak: 20-50 mg/L (traditional dosing) |
Use: | Monitor therapeutic drug level. Half-life is 4-10 h (adult); 2-3 h (child); 6-10 h (neonate). |
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