Vancomycin


Abbrev Code:VANC   
Order Code:LAB3870Order Name:Vancomycin
Methodology:Roche: Kinetic interaction of microparticles in a solution (KIMS)
Vista: Turbidmetric rate
Grand Itasca: Homogenous enzyme immunoassay
Woodwinds: Chemiluminescent microparticle immunoassay (CMIA)
CPT Codes: 80202 x1, 80202 x
Turnaround Time:Performed and reported 24 hours/day.
Associated Links:

Roche Go Live Schedule



Collection Instructions

Specimen:Blood
Optimal Volume:2.5 mL
Minimum\Peds Volume:0.6 mL; pediatric patients only: 0.4 mL in green (lithium heparin, no gel)
Collection Instructions:Chemistry Tests Containers Chart
Trough levels: Collect immediately prior to next dose. Peak levels: collect 2 hours after the end of IV infusion; 3-4 hours if decreased renal function.
Causes for Rejection:Collection in a gel tube.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot within 2 hours of collection 1.25 mL, 0.2 mL minimum (adult) 0.1 mL minimum (peds). Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:48 hours at room temperature; 14 days refrigerated; 12 months frozen. Can be frozen/thawed up to 5 times.
Test Performed at or Referral Lab Chemistry  (Grand Itasca, Northland, Range, Roche-Lakes, Roche-Ridges, Roche-St. John's, Roche-UMMC East, Southdale, UMMC/UMMCH-West Bank, Woodwinds)


Interpretive

Critical Range:Greater than 25 mg/L
Therapeutic Range:Roche: Trough: 10-15 ug/mL; Peak 20-40 ug/mL
All others: Trough: 8-20 mg/L; Peak: 20-50 mg/L (traditional dosing)
Use:Monitor therapeutic drug level. Half-life is 4-10 h (adult); 2-3 h (child); 6-10 h (neonate).


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