Cryptococcal Antigen

Abbrev Code:CRYPTAG   
Order Code:LAB1194Order Name:Cryptococcal Antigen
Methodology:Lateral flow
CPT Codes: 87899 x1
Test Includes:Screen for Cryptococcal Antigen and titer if positive.
Turnaround Time:Performed 24 hours/day. If positive, titer performed Mon-Fri, 0730-1500.
Special Instructions:Cryptococcal antigen testing on CSF should be accompanied by a fungal culture. A fungal culture will be added to all CSF which test positive for Cryptococcal antigen and all non-Outreach CSF which test negative for Cryptococcal antigen if not already ordered.

Collection Instructions

Specimen:CSF or blood
Optimal Volume:1 mL CSF, 4 mL blood
Minimum\Peds Volume:0.5 mL CSF, 1.2 mL blood
Container:CSF Tubes, Red or gold (gel)
Alternate Containers: See Collection Instructions, Red (gel)
Collection Instructions:Collect blood in red or gold (gel) tube. Alternate containers: red (gel) tube; collect CSF in sterile container
Causes for Rejection:Gross hemolysis; lipemia; turbidity. For optimal results, sterile non-hemolyzed serum should be used.

Processing and Shipping

Specimen Processing:Blood: Centrifuge and aliquot 1.8 mL serum (0.5 mL minimum) and store at refrigerated temperature. CSF: Store in a sterile container at refrigerated temperature.
Shipping Instructions:Ship to arrive within 72 hours of collection at refrigerated temperature.
Test Performed at or Referral Lab Infectious Diseases Diagnostic Laboratory   (UMMC East Bank)


Critical Range:Positive
Reference Range:Negative
Use:Establish the presence of Cryptococcus neoformans antigen.

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