Smith (ENA) Aby, IgG
| Sunquest Code: | SMIGG | ||
| Epic Code: | LAB6370 | Epic Name: | Smith ENA AB IGG |
| Synonyms: | ENA (Smith) Antibodies; Extractable Nuclear Antigen (Smith) Antibody | ||
| Methodology: | Multiplex flow immunoassay | ||
| Turnaround Time: | Performed Mon-Fri; results reported the same day. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.9 mL |
| Container: | Red or gold (gel) (Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel)) |
| Causes for Rejection: | Gross hemolysis. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 7 days. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Test Performed at or Referral Lab | Specialty Core (UMMC-East Bank) |
Interpretive
| Reference Range: |
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| Use: | Smith antibody is very specific for SLE but only occurs in 30-35% of SLE cases. The presence of antibodies to Smith is often associated with renal disease. |
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