Smith (ENA) Aby, IgG


Abbrev Code:SMIGG   
Order Code:LAB6370Order Name:Smith ENA AB IGG
Synonyms:ENA (Smith) Antibodies; Extractable Nuclear Antigen (Smith) Antibody
Methodology:Fluorescent enzyme immunoassay
CPT Codes: 86235 x1
Turnaround Time:Performed Mon-Fri; results reported the same day.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.9 mL
Container:Red or gold (gel)
Alternate Containers: Purple (EDTA), Red (no gel)
Causes for Rejection:Gross hemolysis.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 14 days.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Endocrine  (UMMC-East Bank)


Interpretive

Reference Range:
Negative Less than 7.0 U/mL
Positive Greater than 10 U/mL
Use:Smith antibody is very specific for SLE but only occurs in 30-35% of SLE cases. The presence of antibodies to Smith is often associated with renal disease.


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