Smith (ENA) Aby, IgG
| Abbrev Code: | SMIGG | ||
| Order Code: | LAB6370 | Order Name: | Smith ENA AB IGG |
| Synonyms: | ENA (Smith) Antibodies; Extractable Nuclear Antigen (Smith) Antibody | ||
| Methodology: | Fluorescent enzyme immunoassay | ||
| CPT Codes: | 86235 x1 | ||
| Turnaround Time: | Performed Mon-Fri; results reported the same day. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.9 mL |
| Container: | Red or gold (gel) Alternate Containers: Purple (EDTA), Red (no gel) |
| Causes for Rejection: | Gross hemolysis. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 14 days. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Test Performed at or Referral Lab | UM Specialty Core/Prot/Endo (Phadia ELiA G) |
Interpretive
| Reference Range: |
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| Use: | Smith antibody is very specific for SLE but only occurs in 30-35% of SLE cases. The presence of antibodies to Smith is often associated with renal disease. |
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