Carbamazepine Total


Sunquest Code:CARB  
Epic Code:LAB21Epic Name:Carbamazepine Total
Synonyms:Tegretol
Methodology:Turbidmetric rate
Grand Itasca: Homogenous enzyme immunoassay
St Johns/St Joseph: ChemFlex
Turnaround Time:Performed and reported 24 hours/day.


Collection Instructions

Specimen:Blood
Optimal Volume:2.5 mL
Minimum\Peds Volume:0.6 mL
Container:Grand Itasca - Green (lithium heparin, gel), Red (no gel), St Johns/St Joseph/Woodwinds-Green (lithium heparin, no gel) (Grand Itasca - Red (no gel), St Johns/St Joseph/Woodwinds - Red (no gel))
Collection Instructions:Trough level is preferred; collect immediately before dose. It is advisable to monitor at the same time in dosing schedule.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot within 2 hours of collection 1.25 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature. Alternatively, ship on dry ice.
Test Performed at or Referral Lab Chemistry  (Range, UMMC-East Bank, Lakes, Ridges, Southdale, UMMC/UMMCH-West Bank, Grand Itasca, St. Joseph's, St. John's)


Interpretive

Critical Range:St Johns/St Joseph: Greater than 12 ug/mL
All other sites: Greater than 15 mg/L
Therapeutic Range:4-12 mg/L (parent); 0.4-4.0 mg/L (10,11 epoxide-metabolite); serum values may be 10% lower than plasma values.
St Johns/St Joseph: None
Use:Monitor carbamazepine therapy.


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