Carbamazepine Total
| Sunquest Code: | CARB | ||
| Epic Code: | LAB21 | Epic Name: | Carbamazepine Total |
| Synonyms: | Tegretol | ||
| Methodology: | Turbidmetric rate
Grand Itasca: Homogenous enzyme immunoassay St Johns/St Joseph: ChemFlex |
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| Turnaround Time: | Performed and reported 24 hours/day. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.5 mL |
| Minimum\Peds Volume: | 0.6 mL |
| Container: | Grand Itasca - Green (lithium heparin, gel), Red (no gel), St Johns/St Joseph/Woodwinds-Green (lithium heparin, no gel) (Grand Itasca - Red (no gel), St Johns/St Joseph/Woodwinds - Red (no gel)) |
| Collection Instructions: | Trough level is preferred; collect immediately before dose. It is advisable to monitor at the same time in dosing schedule. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot within 2 hours of collection 1.25 mL, 0.2 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. Alternatively, ship on dry ice. |
| Test Performed at or Referral Lab | Chemistry (Range, UMMC-East Bank, Lakes, Ridges, Southdale, UMMC/UMMCH-West Bank, Grand Itasca, St. Joseph's, St. John's) |
Interpretive
| Critical Range: | St Johns/St Joseph: Greater than 12 ug/mL
All other sites: Greater than 15 mg/L |
| Therapeutic Range: | 4-12 mg/L (parent); 0.4-4.0 mg/L (10,11 epoxide-metabolite); serum values may be 10% lower than plasma values.
St Johns/St Joseph: None |
| Use: | Monitor carbamazepine therapy. |
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