GM-1 Antibody Panel
| Sunquest Code: | GM1PAN | ||
| Epic Code: | LAB3508 | Epic Name: | GM1 Antibody Panel |
| Synonyms: | GM1; Ganglioside-monosialic Acid Antibody; GM 1 Antibody Panel; GM1 Antibody Panel | ||
| Methodology: | Enzyme-linked immunosorbent assay | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-4 days. | ||
| Compliance: | This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 0.6 mL |
| Minimum\Peds Volume: | 0.4 mL |
| Container: | Red or gold (gel) (Red (no gel)) |
| Causes for Rejection: | Severely lipemic, hemolyzed or icteric specimens, plasma, CSF or other body fluids. Room temperature specimens. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 0.3 mL, 0.1 mL minimum within 2 hours of collection. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 50591 (GM1 PAN) |
Interpretive
| Reference Range: |
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| Use: | Elevated antibody levels to ganglioside-monosialic acid (GM1) and the neutral glycolipid, asialo GM1 are associated with motor or sensorimotor neuropathies, particularly multifocal motor neuropathy. Anti-GM1 may occur as IgM (polyclonal or monoclonal) or IgG antibodies. These antibodies may also be found in patients with diverse connective tissue diseases as well as normal individuals. These tests by themselves are not diagnostic and should be used in conjunction with other clinical parameters to confirm disease. |
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