Cystine, Leukocyte - Collect Mon-Thurs only. Must be delivered to UMMC Labs by 1500.
| Abbrev Code: | WBCYS | ||
| Order Code: | LAB3879 | Order Name: | Cystine, Leukocyte |
| Synonyms: | White Blood Cell Cystine; 1/2 Cystine; Leukocyte Cystine | ||
| Methodology: | Tandem mass spectrometry; granulocyte half-cystine | ||
| CPT Codes: | 82131 x1 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Thur; results are reported within 2 weeks. | ||
| Special Instructions: |
This test must be shipped the same day it is collected. Include a completed UCSD Biochemical Genetics Request form (see Associated Links) with each sample including the exact collection time and the time of the patient's last medication.
Diagnostic specimens require a control sample from an unrelated normal individual collected, processed and shipped in parallel. Patient and control sample must be refrigerated within 1 hour. Collect specimen on wet ice. Do not use chemical ice packs or allow to freeze. |
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| Associated Links: | |||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 5 mL |
| Minimum\Peds Volume: | 3 mL |
| Container: | Yellow (ACD, Solution A) tube available from laboratory |
| Collection Instructions: |
Collect specimen on wet ice. Do not use chemical ice packs or allow to freeze.
Optimal collection time is immediately prior to the next dose (trough level). Collect Mon-Thurs only and deliver to UMMC labs by 1500. West Bank: Send to Sendouts Bench STAT with STAT sticker, or hand-deliver directly to Sendouts Bench for prompt refrigeration. A control sample from an unrelated normal individual must be obtained at the same time as the patient sample for diagnostic specimens. |
| Causes for Rejection: | Clotted or frozen specimens or specimens not refrigerated within 1 hour of collection. Diagnostic specimens arriving without a control sample. |
Processing and Shipping
| Specimen Processing: | Refrigerate patient sample and control within 1 hour of collection. Do not process. |
| Shipping Instructions: | Ship in a STAT bag on wet ice. Samples must arrive in East Bank Core Lab/Sendouts or ACL West Bank, Mon-Thur 0700-1500, to be sent to UCSD the same day. |
| Stability: | |
| Test Performed at or Referral Lab | Lab Sendouts (University of California, San Diego) |
Interpretive
| Reference Range: | When blood is collected immediately prior to the medication dose, a value of <1.9 nmol/mg protein in granulocytes is found in >99% (the "3 sigma value") of samples from (asymptomatic) cystinosis carriers. |
| Use: | To monitor cystinotic patients taking medication for cystinosis. |
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