Abbrev Code:ARMISC   
Order Code:LAB4909Order Name:Laboratory Miscellaneous Order
Order Instructions:Not intended to be a standalone test. Troponin T (LAB8259) is the recommended test for diagnosis and management of acute coronary syndromes.
Methodology:Quantitative Electrochemiluminescent Immunoassay
CPT Codes: 83874 x1
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 2 days.

This test uses an in vitro diagnostic (IVD) that has been cleared or approved by the FDA.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:0.6 mL
Container:Red or gold (gel)
Alternate Containers: Green (lithium heparin, no gel), Green (lithium heparin, gel), Purple (EDTA), Red (no gel)
Causes for Rejection:  Grossly hemolyzed specimens.

Processing and Shipping

Specimen Processing:Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Aliquot 1 mL serum or plasma, 0.2 mL minimum. Store refrigerated.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells, 8 days at room temperature; 14 days refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:0020224


Reference Range:Female: ≤ 58 ng/mL
Male: ≤ 72 ng/mL
Use: Because myoglobin is found in high concentrations in myocardium, it is a sensitive but not specific marker of cardiac injury. Elevations can also occur due to skeletal muscle release or abnormal renal function (i.e., decreased clearance). Myoglobin should not be used for patients who have sustained traumas or had IM injections. Myoglobin is detectable 2 hours after coronary occlusion with peak levels occurring at 9-12 hours, and return to normal at 24-36 hours. Rapid clearance (half life = 8.9 ± 1.5 minutes) explains the rising and falling (staccato pattern) values observed in some patients with infarction, which most likely represents cyclical opening and closing of the infarct-related coronary artery. For this reason, a single negative myoglobin does not always exclude acute infarction.

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