Coccidioides Antibody by CF

Abbrev Code:CIAB   
Order Code:LAB3379Order Name:Coccidioides Antibody
Synonyms:Fungal Antibody, Coccidioides; Fungus; San Joaquin Fever; Valley Fever
Methodology:Complement fixation
CPT Codes: 86635 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 2-4 days.
Special Instructions:Parallel testing is preferred. Label samples as acute or convalescent. Convalescent sample must be sent within 30 days of acute sample.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:1 mL
Container:Red or gold (gel)
Alternate Containers: Red (no gel)
Causes for Rejection:Hemolyzed, icteric or lipemic specimens.

Processing and Shipping

Specimen Processing:Centrifuge and aliquot ASAP or within 2 hours of collection, 1 mL, 0.4 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:50170


Reference Range:Less than 1:2 titer

Any titer suggests past or current infection. However, greater than 30% of cases with chronic residual pulmonary disease have negative Compliment Fixation tests. Titers of less than 1:32 may indicate past infection or self-limited disease; anticoccidial CF antibody titers in excess of 1:16 may indicate disseminated infection, CF serology may be used to follow therapy.
Use:CF measures both IgM and IgG. As single antibody titers are generally not diagnostic, paired samples are preferred. Acute and convalescent samples (drawn at least 21 days apart) showing at least a four-fold rise in titer, are diagnostic.

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