Ethosuximide Level


Abbrev Code:ETHO   
Order Code:LAB1156Order Name:Ethosuximide
Synonyms:Zarontin
Methodology:Quantitative enzyme immunoassay
CPT Codes: 80168 x1, 80168 x1
Turnaround Time:Specimens are sent to the reference laboratory Sun-Sat; results are reported within 1-5 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:1.2 mL
Container:Red (no gel)
Alternate Containers: Purple (EDTA)
Collection Instructions:Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Causes for Rejection:Whole blood; gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution).


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.5 mL minimum, serum or plasma. Store at refrigerated temperature.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 5 days at room temperature; 1 week refrigerated; 2 months frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2010358


Interpretive

Critical Range:Toxic: >150 μg/mL
Therapeutic Range:40-100 µg/mL
Use:The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Toxic concentrations may cause dizziness, drowsiness and anorexia. The incidence of adverse reactions is low; however, life-threatening agranulocytosis and fatal pancytopenia have been reported.


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