Ethosuximide Level
| Abbrev Code: | ETHO | ||
| Order Code: | LAB1156 | Order Name: | Ethosuximide Level |
| Synonyms: | Zarontin | ||
| Methodology: | Quantitative enzyme immunoassay | ||
| CPT Codes: | 80168 x1, 80168 x1 | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Sun-Sat; results are reported within 2-6 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 1.2 mL |
| Container: | Red (no gel) Alternate Containers: Purple (EDTA) |
| Collection Instructions: | Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. |
| Causes for Rejection: | Whole blood; gel separator tubes, light blue (citrate) or yellow (SPS or ACD solution). |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 1 mL, 0.5 mL minimum, serum or plasma. Store at refrigerated temperature. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | After separation from cells: 5 days at room temperature; 1 week refrigerated; 2 months frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 2010358 |
Interpretive
| Critical Range: | Toxic: >150 μg/mL |
| Therapeutic Range: | 40-100 µg/mL |
| Use: | The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Toxic concentrations may cause dizziness, drowsiness and anorexia. The incidence of adverse reactions is low; however, life-threatening agranulocytosis and fatal pancytopenia have been reported. |
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