Leukocyte Adhesion Deficiency Panel
| Abbrev Code: | ARMISC | ||
| Order Code: | LAB4909 | Order Name: | Send Outs Misc Test |
| Synonyms: | CD11a; CD11b; CD15s; CD18; FLOLAD; LAD; Beta 2 Integrins | ||
| Methodology: | Flow cytometry | ||
| CPT Codes: | 86356 x4 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Fri; results are reported within 1-3 days. | ||
| Special Instructions: | Sample must be assayed within 48 hours of collection. Results of a CBC and differential, including an eosinophil and basophil count, must be sent with the whole blood specimen. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 5 mL |
| Minimum\Peds Volume: | 1 mL |
| Container: | Green (sodium heparin, no gel) Alternate Containers: Purple (EDTA) |
| Causes for Rejection: | Clotted, hemolyzed or frozen specimens. Specimen received >48 hours after collection. |
Processing and Shipping
| Specimen Processing: | Do not process. |
| Shipping Instructions: | Ship overnight at refrigerated temperature. Specimen must be analyzed within 48 hours of collection. |
| Stability: | 48 hours at room temperature or refrigerated. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 2004359 |
Interpretive
| Reference Range: |
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| Use: | The Leukocyte Adhesion Deficiency Panel measures the receptors of CD11a, CD11b, CD15 and CD18 normally found on neutrophils. The percentage of patient neutrophils bearing these receptors is reported. Decreased values outside of the reference interval may correlate with abnormal neutrophil function. For example, CD11 and CD18 are decreased or absent in Leukocyte Adhesion Deficiency (LAD) type I and CD15 is decreased or absent in LAD type II. |
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