Anti-Neutrophil Cytoplasmic Antibody (ANCA), IgG by IFA with Reflex to Titer
| Abbrev Code: | ANCAF | ||
| Order Code: | LAB8038 | Order Name: | ANCA IGG by IFA with Reflex to Titer |
| Synonyms: | Granulomatosis and Polyangiitis; pANCA; cANCA; ANCAB | ||
| Methodology: | Indirect fluorescent antibody | ||
| CPT Codes: | 86036 x1, 86036 x1, 86037 x1, 86037 x1 | ||
| Turnaround Time: | Performed Mon-Fri; results are reported within 2 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.6 mL |
| Container: | Red or gold (gel) Alternate Containers: Red (no gel) |
| Causes for Rejection: | Severely lipemic; hemolyzed; plasma, CSF, urine, and other body fluids. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 1 mL, 0.2 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Test Performed at or Referral Lab | UM Specialty Core/Prot/Endo (Europattern E) |
Interpretive
| Reference Range: |
Less than 1:10
|
| Use: | Anti-Neutrophil Cytoplasmic Antibodies (C-ANCA = granular cytoplasmic staining; P-ANCA = perinuclear staining) are found in the serum of over 90% of patients with certain necrotizing systemic vasculitides, and usually in less than 5% of patients with collagen vascular disease or arthritis. |
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