PSA Total and Free
| Abbrev Code: | FPSA | ||
| Order Code: | LAB171 | Order Name: | PSA Total and Free |
| Synonyms: | Prostatic Specific Antigen; PSA Free; PSA Tumor Marker; PSA Percent Free | ||
| Methodology: | Electrochemiluminescence immunoassay (ECLIA) | ||
| CPT Codes: | 84153 x1, 84153 x1, 84154 x1, 84154 x1 | ||
| Turnaround Time: | Testing is performed daily. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.5 mL |
| Minimum\Peds Volume: | 0.6 mL |
| Container: | Green (lithium heparin, gel) Alternate Containers: Green (lithium heparin, no gel), Green (lithium heparin) on ICE, Red (no gel), Red or gold (gel) |
| Causes for Rejection: | Grossly hemolyzed samples. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot within 4 hours of collection, 1.25 mL, 0.2 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature; alternatively ship on dry ice. |
| Stability: | 7 days refrigerated; up to 4 months frozen at -80°C. |
| Test Performed at or Referral Lab | Chemistry (Roche-UMMC East) |
Interpretive
| Reference Range: | By report. Results include PSA-Free, PSA, PSA-Percent Free.
Roche Free PSA method in conjunction with the Roche tumor marker method to determine the free PSA percentage. The free PSA percentage is an aid in distinguishing prostate cancer from benign prostatic conditions in men age 50 and older with a total PSA between 3 and 10 ng/mL and negative digital rectal examination findings. Prostatic biopsy is required for the diagnosis of cancer. When Total PSA concentration is in the range of 4.0-10.0 ng/mL, the probability of finding prostate cancer on needle biopsy is:
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