Fibrinogen Activity
| Abbrev Code: | FIBR | ||
| Order Code: | LAB314 | Order Name: | Fibrinogen Activity |
| Methodology: | Electromagnetic clot detection | ||
| CPT Codes: | 85384 x1 | ||
| Test Includes: | |||
| Turnaround Time: | Performed and reported 24 hours/day. | ||
| Associated Links: | Specimen Collection and Processing for Coagulation Specimens |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.7 mL (in 3 mL tube) - filled to fill line on the tube |
| Minimum\Peds Volume: | 1.8 mL (in 2 mL tube) - filled to fill line on the tube |
| Container: | Blue Na Citrate, 3.2% - fill to fill line on tube |
| Collection Instructions: | If the patient's hematocrit is >55%, contact laboratory to obtain a special tube. If using a butterfly needle, a waste tube must be collected before the blue top. |
| After Care: | If the patient has a coagulation abnormality, apply direct pressure to the puncture site for 10 minutes; apply a pressure dressing. Instruct the patient to leave the bandage on for 12 hours. |
| Causes for Rejection: | Underfilled tubes, overfilled tubes, clotted specimens, specimens collected in 3.8% buffered citrate.
Grand Itasca: Whole blood specimen not processed within 1 hour or unopened tubes (centrifuged) greater than 24 hours. All other Fairview sites: Whole blood specimens greater than 8 hours old or not processed appropriately within 8 hours of collection. |
Processing and Shipping
| Specimen Processing: | Send whole blood or platelet poor plasma. See Associated Link for additional processing instructions. |
| Shipping Instructions: | Whole blood specimens must arrive within 8 hours. If greater than 8 hours is required for transport, follow specimen processing instructions and ship frozen plasma on dry ice. |
| Test Performed at or Referral Lab | Coagulation (CSC Maple Grove, CSC Mpls, Grand Itasca, Lakes, Northland, Range, Ridges, Southdale, St. John's, UMMC East Bank, UMMC/UMMCH-West Bank, Woodwinds) |
Interpretive
| Critical Range: | Less than 100 mg/dL |
| Reference Range: | 170 - 490 mg/dL |
| Use: | This method is sensitive to functional fibrinogen and insensitive to non-clottable fibrinogen and fibrin derivatives.
The presence of a direct thrombin inhibitor (e.g., argatroban, bivalirudin, dabigatran) or high levels of heparin may interfere in the assay for fibrinogen, potentially causing a false lowering of the result. |
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