Fibrinogen Activity

Abbrev Code:FIBR   
Order Code:LAB314Order Name:Fibrinogen Activity
Methodology:Electromagnetic clot detection
CPT Codes: 85384 x1
Test Includes:
Turnaround Time:Performed and reported 24 hours/day.
Associated Links:

Specimen Collection and Processing for Coagulation Specimens

Collection Instructions

Optimal Volume:2.7 mL (in 3 mL tube) - filled to fill line on the tube
Minimum\Peds Volume:1.8 mL (in 2 mL tube) - filled to fill line on the tube
Container:Blue Na Citrate, 3.2% - fill to fill line on tube
Collection Instructions:If the patient's hematocrit is >55%, contact laboratory to obtain a special tube. If using a butterfly needle, a waste tube must be collected before the blue top.
After Care:If the patient has a coagulation abnormality, apply direct pressure to the puncture site for 10 minutes; apply a pressure dressing. Instruct the patient to leave the bandage on for 12 hours.
Causes for Rejection:Underfilled tubes, overfilled tubes, clotted specimens, specimens collected in 3.8% buffered citrate.
Grand Itasca: Whole blood specimen not processed within 1 hour or unopened tubes (centrifuged) greater than 24 hours.
All other Fairview sites: Whole blood specimens greater than 8 hours old or not processed appropriately within 8 hours of collection.

Processing and Shipping

Specimen Processing:Send whole blood or platelet poor plasma. See Associated Link for additional processing instructions.
Shipping Instructions:Whole blood specimens must arrive within 8 hours. If greater than 8 hours is required for transport, follow specimen processing instructions and ship frozen plasma on dry ice.
Test Performed at or Referral Lab Coagulation  (CSC Maple Grove, CSC Mpls, Grand Itasca, Lakes, Northland, Range, Ridges, Southdale, St. John's, UMMC East Bank, UMMC/UMMCH-West Bank, Woodwinds)


Critical Range:Less than 100 mg/dL
Reference Range:170 - 490 mg/dL
Use:This method is sensitive to functional fibrinogen and insensitive to non-clottable fibrinogen and fibrin derivatives.

The presence of a direct thrombin inhibitor (e.g., argatroban, bivalirudin, dabigatran) or high levels of heparin may interfere in the assay for fibrinogen, potentially causing a false lowering of the result.

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