Sirolimus
| Sunquest Code: | RAPA | ||
| Epic Code: | LAB875 | Epic Name: | Sirolimus Level |
| Order Instructions: | Comment last dose information. Do not cancel this test if the specimen is frozen, comment "Specimen frozen" when test requesting. | ||
| Synonyms: | Rapamune; Rapamycin | ||
| Methodology: | Liquid chromatography/tandem mass spectrometry | ||
| Turnaround Time: | Performed and reported daily if received in Drug Analysis by 9:30 am. For levels outside of this time frame, contact Drug Analysis at 612-273-5838. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.4 mL |
| Container: | Purple (EDTA) |
| Collection Instructions: | Usual sampling time is immediately prior to next dose, but no sooner than 2 hours before. |
| Causes for Rejection: | Clotted specimen. |
Processing and Shipping
| Specimen Processing: | Do not process whole blood. Store at room temperature or refrigerated. |
| Shipping Instructions: | Ship at room temperature.
UMMC-West Bank only: Send STAT. |
| Stability: | Up to 28 days at room temperature (19-26ºC) or refrigerated (2-8ºC). For longer storage, freeze at -10ºC or colder. |
| Test Performed at or Referral Lab | Drug Analysis (UMMC-East Bank) |
Interpretive
| Critical Range: | Greater than 20 ug/L | ||||||||||||||||
| Therapeutic Range: |
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| Use: | Therapeutic drug monitoring and to assess toxicity. |
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