Intraoperative Parathyroid Hormone, Intact


Abbrev Code:PTHOR   
Order Code:LAB3700Order Name:Parathormone Intact Intraoperative
Order Instructions:FRH: must be scheduled 2-3 days before scheduled surgery. Call the main lab (952-892-2085). UMMC: OR must call Chemistry 612-273-3966 when specimen is drawn. OR will bring specimen directly to Acute Care Receiving.
Synonyms:Parathormone; PTH, Intact
Methodology:Chemiluminescent immunoassay
CPT Codes: 83970 x1
Turnaround Time:30 minutes


Collection Instructions

Specimen:Blood
Optimal Volume:3 mL
Minimum\Peds Volume:1.0 mL
Container:Purple (EDTA), St Johns/St Joseph/Woodwinds - Purple (EDTA)
Causes for Rejection:PTH is not stable in a red/black top tube.
Contraindications:Large doses of biotin (10 mg or more per day) may cause clinically significant interference in PTHI levels. If interference is suspected, it is strongly recommended that biotin is discontinued for at least one week prior to retesting.


Processing and Shipping

Specimen Processing:Process immediately. (At UMMC give directly to Chemistry for processing). Centrifuge and aliquot 1.5 mL, 0.4 mL minimum. Store plasma refrigerated; do not freeze. Serum is not recommended, but accepted if separated from cells within 2 hours of collection.
Shipping Instructions:Ship plasma at refrigerated temperature in a STAT bag.
Stability:8 hours at room temperature; 72 hours refrigerated; 8 months frozen.
Test Performed at or Referral Lab Chemistry  (UMMC East, Ridges, St. Joseph's, St. John's, Woodwinds)


Interpretive

Reference Range:18-80 pg/mL.
A greater than 50% drop in PTH value 10 minutes post-resection indicates that all hypersecreting tissue has been removed.

FRH: 
Asian 8.7-79.6 pg/mL
Caucasian 12-64 pg/mL
Other races Normal range is not specified
 
Use:Confirmation of successful removal of hyperfunctioning parathyroid tissue.


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