Intraoperative Parathyroid Hormone, Intact

Abbrev Code:PTHOR   
Order Code:LAB3700Order Name:Parathormone Intact Intraoperative
Order Instructions:Ridges: Must be scheduled 2-3 days before scheduled surgery. Call the main lab (952-892-2085). UMMC: OR must call Chemistry 612-273-3966 when specimen is drawn. OR will bring specimen directly to Acute Care Receiving.
Synonyms:Parathormone; PTH, Intact
Methodology:Roche: Electrochemiluminescence immunoassay (ECLIA)
Architect: Chemiluminescent microparticle immunoassay (CMIA)
CPT Codes: 83970 x1, 83970 x1
Turnaround Time:30 minutes from receipt of sample.
Associated Links:

Roche Go Live Schedule

Collection Instructions

Optimal Volume:3 mL
Minimum\Peds Volume:1.0 mL
Collection Instructions:Chemistry Tests Containers Chart
Causes for Rejection:PTH is not stable in a red/black top tube.
Contraindications:Large doses of biotin (10 mg or more per day) may cause clinically significant interference in PTHI levels. If interference is suspected, it is strongly recommended that biotin is discontinued for at least one week prior to retesting.

Processing and Shipping

Specimen Processing:Process immediately. (At UMMC give directly to Chemistry for processing). Centrifuge and aliquot 1.5 mL, 0.4 mL minimum. Store plasma refrigerated; do not freeze. Serum is not recommended, but accepted if separated from cells within 2 hours of collection.
Shipping Instructions:Ship plasma at refrigerated temperature in a STAT bag.
Stability:8 hours at room temperature; 72 hours refrigerated; 8 months frozen.
Test Performed at or Referral Lab Chemistry  (Roche-CSC Mpls, Roche-Lakes, Roche-Ridges, Roche-Southdale, Roche-St. John's, Roche-UMMC East, Woodwinds)


Reference Range:Roche: 15-65 pg/mL
Architect: 10-82 pg/mL  
All: A greater than 50% drop in PTH value 10 minutes post-resection indicates that all hypersecreting tissue has been removed.
Use:Confirmation of successful removal of hyperfunctioning parathyroid tissue.

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