Herpes Simplex Virus (HSV) Type 1 and 2, IgG

Sunquest Code:H12IGG  
Epic Code:LAB6381Epic Name:Herpes Simplex Virus (HSV) 1 and 2, IgG
Synonyms:HSV 1 and 2, IgG Antibody; Glycoprotein G-Specific Antibodies; HerpesSelect; HSV1; HSV2; H12IGG; HSV-1; HSV-2
Methodology:Multiplex flow immunoassay
Turnaround Time:Performed Mon-Fri; results are reported the same day.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:0.9 mL
Container:Red or gold (gel) (Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel))
Causes for Rejection:Gross hemolysis

Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 7 days.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Specialty Core  (UMMC-East Bank)


Reference Range:

Less than 0.9 AI

Negative, suggests no immunologic exposure.

0.9-1.0 AI

Equivocal, please recollect.

1.1 AI or greater

Positive, suggests immunologic exposure.

Antibody index (AI) values reflect qualitative changes in antibody concentration that cannot be directly associated with clinical condition or disease state.



HSV-1 has been implicated in cold sores and genital herpes. HSV-2 causes 70 to 90 percent of primary genital herpes infections with HSV-1 causing the remainder. HSV-2 genital infections recur in greater than 95% of cases, with up to four to five recurrences per year. Genital HSV-1 averages only one recurrence per year in about half of the cases.


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