Histone Antibody, IgG
| Sunquest Code: | HSTON | ||
| Epic Code: | LAB3548 | Epic Name: | Histone Antibody IgG |
| Synonyms: | Anti-histone Antibody IgG; Drug Induced SLE | ||
| Methodology: | Enzyme-linked immunosorbent assay | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-4 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 1 mL |
| Minimum\Peds Volume: | 0.8 mL |
| Container: | Red or gold (gel) [Alternate Containers: Red (no gel)] |
| Causes for Rejection: | Grossly hemolyzed, icteric or lipemic specimens. Plasma or urine. |
Processing and Shipping
| Specimen Processing: | Separate serum from cells ASAP. Centrifuge and aliquot 0.5 mL, 0.3 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 50860 (AHA) |
Interpretive
| Reference Range: |
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| Use: | Histone antibodies are present in 20-55% of idiopathic SLE and 80-95% of drug induced SLE. They occur in less than 20% of other types of connective tissue diseases. |
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