Rickettsia rickettsii Antibody, IgM

Abbrev Code:RICAM   
Order Code:LAB3718Order Name:Rickettsia rickettsii Antibody, IgM
Synonyms:Rocky Mountain Spotted Fever Antibody, IgM; Rickettsia, RMSF
Methodology:Indirect immunofluorescence antibody
CPT Codes: 86757 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-3 days.
Special Instructions:Parallel testing is preferred. Label samples as acute or convalescent. Convalescent specimens must be received within 30 days from receipt of the acute specimens.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:0.8 mL
Container:Red or gold (gel)
Alternate Containers: Red (no gel)
Causes for Rejection:Contaminated, severely lipemic, hemolyzed.

Processing and Shipping

Specimen Processing:Separate serum from cells within 2 hours of collection. Centrifuge and aliquot 1 mL, 0.3 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:50372


Reference Range:

Less than 1:64

Negative: No significant level of Rickettsia rickettsii Antibody IgM detected.

1:64 or greater

Positive: Presence of Rickettsia rickettsii Antibody IgM detected, which may indicate a current or recent infection; however, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection



Use:The CDC does not use IgM results for routine diagnostic testing of Rocky Mountain Spotted Fever, as the response may not be specific for the agent (resulting in false positives) and the IgM response may be persistent from past infection.

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